物理化学学报 >> 1997, Vol. 13 >> Issue (01): 71-73.doi: 10.3866/PKU.WHXB19970115

研究简报 上一篇    下一篇

细胞呼吸爆发的微量量热学研究

谭安民,黄元庆,屈松生   

  1. 武汉大学化学系，武汉 430072|北京医科大学天然药物及仿生药物国家重点实验室，北京 100083|宁夏医学院，银川 750004
  • 收稿日期:1996-07-16 修回日期:1996-09-25 发布日期:1997-01-15
  • 通讯作者: 屈松生

Microcalorimetric Study on the Respiratory Burst of Polymorphonuclear Leukocytes

Tan An-Min,Huang Yuan-Qing,Qu Song-Sheng   

  1. Department of Chemistry,Wuhan University,Wuhan 430072|National Key Laboratory of Natural and Biomimetic Drugs,Beijing 100083|Ningxia Medical University,Yingchuan 650004
  • Received:1996-07-16 Revised:1996-09-25 Published:1997-01-15
  • Contact: Qu Song-Sheng

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关键词: 微量量热学, 热化学, 大鼠多形核白细胞, 呼吸爆发, 佛波酯, 枸杞总黄酮

Abstract:

The heat production of Wistar rat polymorphonuclear leukocytes (PMN) was measured by an LKB 2277 Thermal Activity Monitor. When PMN were activited with phorbol-12-myristate13-acetate (PMA), the respiratory burst was recorded by greatly incr eased heat production. Experiment was also carred out in the present of the inhibitor, Total Flavonoids of Lycium Barbarum L. (TFL). The respiratory burst heat production peak was disappeared, but the heat production curve was higher than that of PMA because TFL increased the metabolic activities of PMN.

Key words: Thermochemistry, Microcalorimetry, Respiratory burst, Polymorphonuclear leukocytes(PMN), Phorbol-12-myristate-13-acetate(PMA), Total Flavonoids of Lycium barbarum L.(TFL)