物理化学学报 >> 2003, Vol. 19 >> Issue (04): 302-306.doi: 10.3866/PKU.WHXB20030404

研究论文 上一篇    下一篇

一类新型手性表面活性剂的研究

黄建滨;高强;王传忠   

  1. 分子动态与稳态结构国家重点实验室,北京大学化学与分子工程学院,北京 100871
  • 收稿日期:2002-07-10 修回日期:2002-09-26 发布日期:2003-04-15
  • 通讯作者: 黄建滨 E-mail:JBHuang@chem.pku.edu.cn

The Research of a Novel Kind of Chiral Surfactant

Huang Jian-Bin;Gao Qiang;Wang Chuan-Zhong   

  1. State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871
  • Received:2002-07-10 Revised:2002-09-26 Published:2003-04-15
  • Contact: Huang Jian-Bin E-mail:JBHuang@chem.pku.edu.cn

摘要: 制备了一对旋光异构的两亲分子L-C10HL(N-(4-癸氧基-2-羟基苯亚甲基)-L-亮氨酸)和D-C10HL(N-(4-癸氧基-2-羟基苯亚甲基)-D-亮氨酸).对相应的表面活性和聚集体研究发现,C10HL与传统羧酸盐表面活性剂有很大的不同,在较高pH时仍具有较高的表面活性和聚集能力.利用荧光激发光谱和圆二色性谱研究了L-C10HL和D-C10HL与环糊精之间的相互作用.

关键词: 手性表面活性剂, 囊泡, 表面活性, 荧光光谱, 圆二色谱

Abstract: A pair of optical isomerism amphiphlic molecules L-C10HL(N-(4-decaoxygen- 2-hydroxybenzene methylene)-L-leucine) and D-C10HL(N-(4-decaoxygen-2-hydroxybenzene methylene)-D-leucine)were synthesized. It was found that these two compounds showed superior surface activity and aggregation capability at higher pH value, which is so different from the traditional carboxylate surfactants. Furthermore, the interaction of L-C10HL and D-C10HL with cyclodextrin was also investigated by fluorescence excitation spectrum and circular dichroism spectrum.

Key words: Chiral surfactant, Vesicle, Surface activity, Fluorescence spectrum,  Circular dichroism spectrum