物理化学学报 >> 2004, Vol. 20 >> Issue (08S): 989-994.doi: 10.3866/PKU.WHXB200408zk15

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均相催化活化杂原子－碳(E－C)键及其与炔烃的加成反应

华瑞茂   

  1. 清华大学化学系,有机光电子与分子工程教育部重点实验室,北京　100084
  • 收稿日期:2004-01-02 修回日期:2004-03-15 发布日期:2004-08-15
  • 通讯作者: 华瑞茂 E-mail:ruimao@mail.tsinghua.edu.cn

Homogeneous Catalytic Activation of Hetero－Carbon Bond and Its Addition to Alkynes

Hua Rui-Mao   

  1. Key Laboratory of Organic Optoelectronics ＆ Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing　100084
  • Received:2004-01-02 Revised:2004-03-15 Published:2004-08-15
  • Contact: Hua Rui-Mao E-mail:ruimao@mail.tsinghua.edu.cn

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摘要： 系统总结了Ni、Pd、Pt、Rh、Cu等过渡金属配合物催化活化Si－C、Sn－C、S－C、Se－C、Cl－C、Br－C等杂原子－碳键及其与炔烃的加成反应.这些新型的炔烃加成反应提供了合成含R3Si、R3Sn、RS、RSe、Cl和Br等活性官能团烯烃化合物的原子经济型一步合成方法.同时加成反应体系具有很高的立体选择性和区域选择性.

关键词: 过渡金属配合物, 杂原子－碳键, 活化, 加成反应, 选择性

Abstract: This paper reviews the transition metal complexes such as Ni, Pd, Pt, Rh, Cu-catalyzed activation of hetero－carbon bonds and the related catalytic addition reactions with alkynes. These new addition reactions provide one-step, atom-economic methods for the preparation of the functionalized alkenes, which have R3Si, R3Sn, RS, RSe, Cl and Br groups. The addition reactions proceed with high stereoselectivities and regioselectivities.

Key words: Transition metal complex, Hetero－Carbon bond, Activation, Addition reaction, Selectivity