物理化学学报 >> 2010, Vol. 26 >> Issue (02): 311-316.doi: 10.3866/PKU.WHXB20100145

胶体及界面化学 上一篇    下一篇

电容法研究卵磷脂/氨基酸/H2O胶束和囊泡体系

刘天晴, 汤瑶, 禹克伟   

  1. 扬州大学化学化工学院, 江苏 扬州 225002
  • 收稿日期:2009-07-01 修回日期:2009-10-12 发布日期:2010-01-26
  • 通讯作者: 刘天晴 E-mail:tqliu@yzu.edu.cn

Study on Lecithin/Amino Acid/H2O Micelle and Liposome Systems by Capacitance Method

LIU Tian-Qing, TANG Yao, YU Ke-Wei   

  1. School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, Jiangsu Province, P. R. China
  • Received:2009-07-01 Revised:2009-10-12 Published:2010-01-26
  • Contact: LIU Tian-Qing E-mail:tqliu@yzu.edu.cn

摘要:

运用电容法研究卵磷脂/氨基酸/H2O胶束和囊泡体系结构与性质. 卵磷脂的临界胶束浓度和囊泡生成浓度可由体系电容-卵磷脂浓度关系曲线求得.随着卵磷脂浓度增加, 体系电容增加, 卵磷脂由胶束形成囊泡. 随着氨基酸浓度增加, 胶束、囊泡半径增大, 体系电容减小. 氨基酸能促进卵磷脂形成胶束和囊泡, 使得卵磷脂临界胶束浓度和囊泡生成浓度减小, 其影响的强弱顺序为组氨酸>色氨酸>>甘氨酸.

关键词: 胶束, 电容, 囊泡, 卵磷脂, 氨基酸

Abstract:

The structures and properties of lecithin/amino acid/H2O micelle and liposome systems were studied using electrical capacitance. The critical micellar concentration and the liposome formation concentration of lecithin can be obtained from the relation of system capacitance with lecithin's concentration. With an increase in lecithin concentration, the capacitance increases and lecithin aggregates from the micelles to liposomes. With the increase of amino acids, the radii of the micelles and liposomes increase but the capacitance decreases. Amino acids can promote micelle and liposome formation as well as decrease the critical micellar concentration and the formation concentration. The sequence of amino acid influence on the capacitance is as follows: histidine>tryptophan>>glycine.

Key words: Micelle, Capacitance, Liposome, Lecithin, Amino acid

MSC2000: 

  • O648