物理化学学报 >> 2011, Vol. 27 >> Issue (01): 255-261.doi: 10.3866/PKU.WHXB20110135

材料物理化学 上一篇    下一篇

溶液环境中CdSeS量子点与金纳米颗粒相互作用

韩荣成1, 喻敏1, 沙印林1,2   

  1. 1. 北京大学医学部基础医学院生物物理系, 北京 100191;
    2. 北京大学前沿交叉学科研究院, 北京 100871
  • 收稿日期:2010-07-29 修回日期:2010-10-21 发布日期:2010-12-31
  • 通讯作者: 沙印林 E-mail:shyl@hsc.pku.edu.cn
  • 基金资助:

    国家重点基础研究发展规划项目(2007CB935801)资助

Interaction between CdSeS Quantum Dots and Gold Nanoparticles in Solution

HAN Rong-Cheng1, YU Min1, SHA Yin-Lin1,2   

  1. 1. Department of Biophysics, School of Basic Medical Sciences, Peking University, Beijing 100191, P. R. China;
    2. Biomed-X Center, Peking University, Beijing 100871, P. R. China
  • Received:2010-07-29 Revised:2010-10-21 Published:2010-12-31
  • Contact: SHA Yin-Lin E-mail:shyl@hsc.pku.edu.cn
  • Supported by:

    The project was supported by the National Key Basic Research Program of China (973) (2007CB935801).

摘要:

选用不同发射波长的合金型CdSeS量子点(QDs), 研究溶液状态下量子点和金纳米颗粒(AuNPs)相互作用及离子强度、pH值、距离等诸多因素对相互作用的影响, 在此基础上对相互作用的机理进行了分析. 在溶液状态下, 金纳米颗粒可以高效地淬灭量子点, Stern-Volmer 淬灭常数Ksv值在108 L·mol-1数量级. 这种淬灭效应与距离、光谱之间叠合程度等密切相关, 受溶液极性、离子强度、pH值的影响较小. 金纳米颗粒与量子点相互作用的机理较为复杂, 以能量转移为主. 研究结果对设计更高效的生物传感器及更全面认识金纳米颗粒与量子点相互作用的机理具有重要意义.

关键词: 量子点, 金纳米颗粒, 淬灭, 能量转移

Abstract:

We studied the interaction between CdSeS quantum dots (QDs) and gold nanoparticles (AuNPs) in solution. We found that the photoluminescence (PL) intensity of the QDs was efficiently quenched by the AuNPs with extraordinarily high Stern-Volmer quenching constant (Ksv) values that approach 108 L·mol-1. The quenching efficiency is strongly related to the spectral overlap and the distance between the QDs and AuNPs and is independent of solvent polaritym, ion strength, and pH value. These results suggest that this superquenching behavior can be attributed to a long-range (Förster-type) energy transfer. Our findings allow for the design of exquisite multiple örster resonance energy transfer (FRET)-based biosensors for the highly sensitive and simultaneous monitoring of multiple molecules in live cells.

Key words: Quantum dots, Gold nanoparticles, Quenching, Energy transfer

MSC2000: 

  • O644