物理化学学报 >> 2012, Vol. 28 >> Issue (05): 993-1011.doi: 10.3866/PKU.WHXB201203023

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磁性氧化铁纳米颗粒——通向肿瘤磁共振分子影像的重要基石

乔瑞瑞1, 曾剑峰1, 贾巧娟1, 杜军2, 沈琳3, 高明远1   

  1. 1. 中国科学院化学研究所, 北京 100190;
    2. 中山大学药学院, 微生物与生化药学实验室, 广州 510080;
    3. 北京大学临床肿瘤学院, 北京肿瘤医院, 北京 100036
  • 收稿日期:2012-01-15 修回日期:2012-02-21 发布日期:2012-04-26
  • 通讯作者: 高明远 E-mail:gaomy@iccas.ac.cn
  • 基金资助:

    国家重点基础研究发展计划(973) (2011CB935800)和国家自然科学基金(81090271, 21003135, 20820102035)资助项目

Magnetic Iron Oxide Nanoparticle——an Important Cornerstone of MR Molecular Imaging of Tumors

QIAO Rui-Rui1, ZENG Jian-Feng1, JIA Qiao-Juan1, DU Jun2, SHEN Lin3, GAO Ming-Yuan1   

  1. 1. Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
    2. Laboratory of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China;
    3. Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100036, P. R. China
  • Received:2012-01-15 Revised:2012-02-21 Published:2012-04-26
  • Contact: GAO Ming-Yuan E-mail:gaomy@iccas.ac.cn
  • Supported by:

    The project was supported by the National Key Basic Research Program of China (973) (2011CB935800) and National Natural Science Foundation of China (81090271, 21003135, 20820102035).

摘要: 本文根据近年来国内外发表的相关研究成果, 总结了磁性氧化铁纳米晶体制备方面的研究进展, 并以磁性氧化铁纳米颗粒在肿瘤磁共振分子影像领域中的应用为背景, 阐述了肿瘤分子影像领域的未来发展趋势.

关键词: 磁性纳米颗粒, 肿瘤, 磁共振, 分子影像, 多模态

Abstract: This review summaries the syntheses and applications of magnetic iron oxide nanocrystals that have been published worldwide. In particular, it discusses the future applications of magnetic iron oxide nanoparticles in molecular imaging of tumors.

Key words: Magnetic nanoparticle, Tumor, Magnetic resonance, Molecular imaging, Multi-modality

MSC2000: 

  • O646