物理化学学报 >> 2006, Vol. 22 >> Issue (12): 1466-1472.doi: 10.1016/S1872-1508(06)60075-2

研究论文 上一篇    下一篇

POPOP诱导环糊精形成纳米管的研究

程祥龙;吴爱华;沈兴海;何永克   

  1. (北京分子科学国家实验室, 北京大学化学与分子工程学院应用化学系, 北京 100871)
  • 收稿日期:2006-05-19 修回日期:2006-07-11 发布日期:2006-12-06
  • 通讯作者: 沈兴海 E-mail:xshen@pku.edu.cn

The Formation of Cyclodextrin Nanotube Induced by POPOP Molecule

CHENG Xiang-Long;WU Ai-Hua;SHEN Xing-Hai;HE Yong-Ke   

  1. (Beijing National Laboratory for Molecular Sciences, Department of Applied Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China)
  • Received:2006-05-19 Revised:2006-07-11 Published:2006-12-06
  • Contact: SHEN Xing-Hai E-mail:xshen@pku.edu.cn

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摘要： 用紫外吸收光谱、稳态荧光、荧光各向异性和动态光散射等方法研究了2,2′-p-亚苯基-双(5-苯基噁唑) (POPOP)分子与环糊精(CD)的相互作用. 结果表明, POPOP分子在浓度较低时与β-CD形成1:2的包合物, 在浓度较高时可以进一步诱导β-CD形成纳米管结构. 同时发现, POPOP分子也可以诱导γ-CD形成纳米管结构. 对比于β-CD, POPOP分子在γ-CD水溶液中的荧光发射峰, 不仅有明显的红移而且也缺失了精细结构, 呈现较宽的大包峰. 这是由于POPOP分子成对进入γ-CD空腔形成了激基缔合物的缘故. pH和温度效应实验进一步表明, POPOP诱导β-CD形成的纳米管在pH大于12和温度高于331 K的环境下不能稳定存在.

关键词: 纳米管, 环糊精, 荧光各向异性, 动态光散射

Abstract: The interaction between 2,2′-p-phenylenebis (5-phenyloxazol) (POPOP) and cyclodextrins (CDs) was investigated using UV-Vis absorption, steady-state fluorescence, and dynamic light scattering (DLS). The results indicated that POPOP could form the 1:2 (guest:host) inclusion complex with β-CD at lower concentrations, which could further form the extended nanotube at higher concentrations. POPOP could also induce the formation of the nanotube of γ-CD. The fluorescence emission of POPOP in aqueous solution of γ-CD showed obvious red shift accompanied by the disappearance of fine structure compared with that in aqueous solution of β-CD, which could be attributed to the formation of the excimer of POPOP in the larger cavity of γ-CD. It was found that at pH greater than 12, the hydrogen bond between the neighboring CDs was destroyed, which led to the collapse of the nanotubular structure. The results also showed that the nanotube structure was not stable at temperatures above 331 K.

Key words: Nanotube, Cyclodextrin, Fluorescence anisotropy, Dynamic light scattering