物理化学学报 >> 1986, Vol. 2 >> Issue (03): 195 -198 .doi: 10.3866/PKU.WHXB19860302

通讯 上一篇    下一篇

0.3 nm分辨率绿豆胰蛋白酶抑制剂Lys活力碎片—牛胰蛋白酶(MBILF-BTRY)复合物的晶体结构分析和分子模型

唐有棋; 曾杰; 陈忠国; 李根培; 卢光莹; 卫新成; 曹天钦; 林光大; 张荣光; 宣建成; 戚正武   

  1. 北京大学物理化学研究所生物系; 上海生物化学研究所
  • 收稿日期:1986-03-20 修回日期:1900-01-01 发布日期:1986-06-15

CRYSTAL STRUCTURE ANALYSIS AND MOLECULAR MODEL OF MUNG BEAN TRYPSIN INHIBITOR LYS ACTIVE FRAGMANT—BOVINE TRYPSIN (MBILFBTRY) COMPLEX AT 0.3 nm RESOLUTION

Tang Youqi; Zeng Jie; Chen Zhongguo; Li Genpei; Lu Guangying; Wei Xincheng; Cao Tienchin; Lin Guangda; Zhang Rongguang; Xuan Jiancheng; Chi Zhengwu   

  1. Institute of Physical Chemistry and Department of Biology, Peking University; Institute of Biochemistry, Academic Sinica, Shanghai
  • Received:1986-03-20 Revised:1900-01-01 Published:1986-06-15

PDF (PC)

1892

赞

Abstract: Crystal structure of MBILF-BTRY complex was successfully solved by molecular replacement method and its 3-dimensional molecular model was thereby derived.
Mung bean trypsin inhibitor belongs to Bowman-Birk inhibitor group, which is by far the most complicated among the ten fundamental groups of serine protease inhibitor. Neither the 3-dimensional structure of Bowman-Birk inhibitor group nor the stereoscopic conformation of its complex with protease has ever been reported. The crystallographic data of MBILF-BTRY complex are found to be a=....