物理化学学报 >> 1992, Vol. 8 >> Issue (05): 647-653.doi: 10.3866/PKU.WHXB19920514

研究论文 上一篇    下一篇

用镧系位移试剂研究L-赖氨酸在水溶液中的结构

王建军; 王晓春; 欧阳一山; 游宇健; 戴安邦   

  1. 南京大学医学院;南京大学配位化学研究所,南京 210008
  • 收稿日期:1990-08-14 修回日期:1992-05-30 发布日期:1992-10-15
  • 通讯作者: 王晓春

The Solution Structure Studies of L-Lysine by Means of NMR Lanthanide Shift Reagent

Wang Jian-Jun; Wang Xiao-Chun; Ouyang Yi-Shan; You Yu-Jian; Dai An-Bang   

  1. Medical College, Nanjing University, Nanjing 210008; Department of Chemistry, Nanjing Univeristy, Nanjing 210008
  • Received:1990-08-14 Revised:1992-05-30 Published:1992-10-15
  • Contact: Wang Xiao-Chun

摘要: 利用镧系位移试剂, 测定了L-赖氨酸在水溶液中的~(13)C-NMR谱并对其进行研究。根据所设计的“自洽迭代”方法, 分离得到了L-赖氨酸中各碳原子的接触位移和偶极位移, 并自偶极位移值拟合得到L-赖氨酸在水溶液中的结构。

关键词: L-赖氨酸, 结构, 镧系位移试剂, 13C-NMR

Abstract: ~(13)C NMR spectral studies have been performed on the structure of the adducts of lanthanide ions and L-lysine using aqueous lanthanide shift reagents. The lanthanide-induced shifts are separated into contact and dipolar components by a new method of separation with a self-consistent manner. The geometry of L-lysine is described by the geometric factors derived from dipolar shifts, optimized by computer search, and checked by Euler transformation.

Key words: L-lysine, Structure, Lanthanide shift reagent, 13C-NMR