物理化学学报 >> 2015, Vol. 31 >> Issue (3): 505-511.doi: 10.3866/PKU.WHXB201501192

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木质素基偶氮聚合物胶体球的制备

邓永红, 刘友法, 张伟健, 邱学青   

  1. 华南理工大学化学与化工学院, 制浆造纸国家重点实验室, 广州 510640
  • 收稿日期:2014-11-19 修回日期:2015-01-16 发布日期:2015-03-06
  • 通讯作者: 邱学青 E-mail:xueqingqiu66@163.com
  • 基金资助:

    国家自然科学基金(21436004, 21374032)资助项目

Formation of Colloidal Spheres from a Lignin-Based Azo Polymer

DENG Yong-Hong, LIU You-Fa, ZHANG Wei-Jian, QIU Xue-Qing   

  1. State Key Laboratory of Pulp and Paper Engineering, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China
  • Received:2014-11-19 Revised:2015-01-16 Published:2015-03-06
  • Contact: QIU Xue-Qing E-mail:xueqingqiu66@163.com
  • Supported by:

    The project was supported by the National Natural Science Foundation of China (21436004, 21374032).

摘要:

利用造纸废液中的碱木素(AL)合成了木质素基偶氮聚合物(AL-azo-COOEt), 并研究其自组装胶体化过程. 木质素偶氮聚合物的成功合成通过核磁共振氢谱(1H NMR)、紫外-可见(UV-Vis)光谱、傅里叶变换红外(FTIR)光谱和元素分析等表征方法得到证实. 激光光散射(LLS)监测了AL-azo-COOEt的胶体化过程, 自组装形成的胶体球利用透射电镜(TEM)、扫描电镜(SEM)、X射线光电子能谱仪(XPS)和元素分析等进行表征. 结果表明,木质素偶氮聚合物通过疏水聚集作用可以形成规整的实心胶体球, 且为内部较疏水外部较亲水性质的结构. 木质素偶氮聚合物胶体球可以包载疏水性药物阿霉素(DOX), 且其缓释性能可以通过缓冲溶液的pH值来调控.

关键词: 碱木素, 偶氮聚合物, 自组装, 胶体球, 包载

Abstract:

2-(4-Ethyl formate phenyl azo) phenol lignin-modified polymer (AL-azo-COOEt), a novel ligninbased azo polymer, has been successfully synthesized from alkali lignin (AL) recovered from pulping black liquor. The micellization process of the AL-azo-COOEt polymer was also studied. The synthetic products were characterized by elemental analysis, Fourier transform infrared (FT- IR) spectra, proton nuclear magnetic resonance (1H NMR) spectroscopy, and ulraviolet-visible (UV-Vis) spectroscopy. The formation of the micelles was monitored by laser light scattering (LLS), and a scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to characterize the surface morphology of the colloidal spheres. X-ray photoelectron spectroscopy (XPS) and elemental analysis were used to obtain the surface element distribution and average element content of the colloidal spheres, respectively. Results show that lignin-based azo polymer AL-azo-COOEt can form uniform solid colloidal spheres by hydrophobic aggregation. Colloidal spheres formed gradually when the water content increased beyond the critical water content (CWC), The CWC has a linear relationship with the logarithm of the initial concentration of AL-azo-COOEt (C0). The colloidal spheres consist of a relatively hydrophobic interior and a relatively hydrophilic surface. The AL-azo-COOEt colloidal spheres can load Doxorubicin (DOX) and the in vitro release can be controlled by adjusting the pH of buffered solution.

Key words: Alkali lignin, Azo polymer, Self-assembly, Colloidal sphere, Micelle loading

MSC2000: 

  • O648