Acta Phys. -Chim. Sin. ›› 1986, Vol. 2 ›› Issue (03): 195-198.doi: 10.3866/PKU.WHXB19860302

• Communication • Previous Articles     Next Articles

CRYSTAL STRUCTURE ANALYSIS AND MOLECULAR MODEL OF MUNG BEAN TRYPSIN INHIBITOR LYS ACTIVE FRAGMANT—BOVINE TRYPSIN (MBILFBTRY) COMPLEX AT 0.3 nm RESOLUTION

Tang Youqi; Zeng Jie; Chen Zhongguo; Li Genpei; Lu Guangying; Wei Xincheng; Cao Tienchin; Lin Guangda; Zhang Rongguang; Xuan Jiancheng; Chi Zhengwu   

  1. Institute of Physical Chemistry and Department of Biology, Peking University; Institute of Biochemistry, Academic Sinica, Shanghai
  • Received:1986-03-20 Revised:1900-01-01 Published:1986-06-15

Abstract: Crystal structure of MBILF-BTRY complex was successfully solved by molecular replacement method and its 3-dimensional molecular model was thereby derived.
Mung bean trypsin inhibitor belongs to Bowman-Birk inhibitor group, which is by far the most complicated among the ten fundamental groups of serine protease inhibitor. Neither the 3-dimensional structure of Bowman-Birk inhibitor group nor the stereoscopic conformation of its complex with protease has ever been reported. The crystallographic data of MBILF-BTRY complex are found to be a=....