Acta Phys. -Chim. Sin. ›› 1996, Vol. 12 ›› Issue (08): 746-750.doi: 10.3866/PKU.WHXB19960814

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Studies on the Antibacterium Effect of D-glucosamine Schiff Base and Its Metal Complexes

Feng Ying,Liu Yi,Xie Chang-Li,Qu Song-Sheng,Le Zhi-Feng,Feng Chang-Jian,Shen Hao-Yu,Zhang Xiang-Cai   

  1. Department of Chemsitry,Wuhan University,Wuhan 430072|Department of Chemistry,Central China Normal University,Wuhan 430070
  • Received:1995-11-13 Revised:1996-03-18 Published:1996-08-15
  • Contact: Qu Song-Sheng

Abstract:

The effects of D-glucosamine schiff base and its metal complexes on the growth of Aerobacter aerogenes were investigated by the microcalorimetry. Among the substances tested. Zn-SG was shown to be the most bacteriostasic, followed by Zn-o-VG and SG (with the Ic50 of 242, 287 and 320 μg•mL-1, respectively). Cu(Ⅱ)-SG showed less inhibitory effect on Aerobacter aerogenes over the concentration rang of 50~300μg•mL-1.

Key words: Microcalorimetry, Aerobacter aerogenes, Schiff base metal complexes, Bacteriostasis