Acta Phys. -Chim. Sin. ›› 1997, Vol. 13 ›› Issue (06): 503-509.doi: 10.3866/PKU.WHXB19970606

• ARTICLE • Previous Articles     Next Articles

Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization

Xiong Ya,Pan Zheng-Jun,Wang Hong,Wu Ding-Quan,Kang Li-Shan,Qu Song-Sheng   

  1. Department of Chemistry,State Key Laboratory of Soft Engineer,Wuhan University,Wuhan 430072
  • Received:1996-09-22 Revised:1996-11-25 Published:1997-06-15
  • Contact: Qu Song-Sheng


The thermokinetic equation (MTD) of mitochondrial metabolism was deduced and the relation between this equation and exponential model was examined. The technology of evolutionary computation was first introduced to the research  of biological thermochemistry. The thermokinetic parameters of some mitochondrial external metabolism were globally optimized with the evolutionary computation program about MTD, which was programmed ourselves, and excellent result was obtained.

Key words: Mitochondria, Evolution computation, Thermokinetics, Global optimum, Microcalorimetry