Acta Phys. -Chim. Sin. ›› 2007, Vol. 23 ›› Issue (10): 1537-1542.doi: 10.3866/PKU.WHXB20071010

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Study on Selective Hydrogenation of Avermectin to Ivermectin over Ir/γ-Al2O3

YANG Peng; FAN Guang-Yin MA Xiao-Yan; LI Rui-Xiang; LI Xian-Jun   

  1. Key Laboratory of Green Chemistry and Technology of the Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China
  • Received:2007-05-07 Revised:2007-06-12 Published:2007-10-01
  • Contact: LI Rui-Xiang E-mail:sculiruixiang@163.com

Abstract: Catalysts Ir/γ-Al2O3 were prepared by impregnating γ-Al2O3 with an aqueous solution or microemulsion solution ofH2IrCl6. The catalystswere characterized by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and transmission electron microscope (TEM). The catalytic performance of the supportediridiumcatalysts for the selective hydrogenation of avermectin to ivermectin was investigated. Compared with active carbon (AC), α-Al2O3, and TiO2, γ-Al2O3 is a better support in this system. Among Ir, Ru, Pd, and Pt supported on γ-Al2O3, the catalyst Ir/γ-Al2O3 showed the best catalytic activity and selectivity to ivermectin. Ir/γ-Al2O3 prepared by means of microemulsion solution showed the best catalytic activity, but the catalytic selectivity to ivermectin was lower that over Ir/γ-Al2O3 modified with PVP (polyvinylpyrrolidone), which exhibited excellent activity as well as good selectivity.

Key words: Supported catalyst, Iridium, Avermectin, Ivermectin, Selective hydrogenation

MSC2000: 

  • O643