Acta Phys. -Chim. Sin. ›› 2011, Vol. 27 ›› Issue (01): 255-261.doi: 10.3866/PKU.WHXB20110135

• PHYSICAL CHEMISTRY OF MATERIALS • Previous Articles     Next Articles

Interaction between CdSeS Quantum Dots and Gold Nanoparticles in Solution

HAN Rong-Cheng1, YU Min1, SHA Yin-Lin1,2   

  1. 1. Department of Biophysics, School of Basic Medical Sciences, Peking University, Beijing 100191, P. R. China;
    2. Biomed-X Center, Peking University, Beijing 100871, P. R. China
  • Received:2010-07-29 Revised:2010-10-21 Published:2010-12-31
  • Contact: SHA Yin-Lin
  • Supported by:

    The project was supported by the National Key Basic Research Program of China (973) (2007CB935801).


We studied the interaction between CdSeS quantum dots (QDs) and gold nanoparticles (AuNPs) in solution. We found that the photoluminescence (PL) intensity of the QDs was efficiently quenched by the AuNPs with extraordinarily high Stern-Volmer quenching constant (Ksv) values that approach 108 L·mol-1. The quenching efficiency is strongly related to the spectral overlap and the distance between the QDs and AuNPs and is independent of solvent polaritym, ion strength, and pH value. These results suggest that this superquenching behavior can be attributed to a long-range (Förster-type) energy transfer. Our findings allow for the design of exquisite multiple örster resonance energy transfer (FRET)-based biosensors for the highly sensitive and simultaneous monitoring of multiple molecules in live cells.

Key words: Quantum dots, Gold nanoparticles, Quenching, Energy transfer


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