Acta Phys. -Chim. Sin. ›› 2016, Vol. 32 ›› Issue (1): 380-390.doi: 10.3866/PKU.WHXB201511193

• ARTICLE • Previous Articles    

Preparation and Property of Gold Nanoparticles from Muliple Self-Assembled Structures as Templates in LA/C14DMAO/H2O System

Lei FENG,Jing-Cheng HAO*()   

  • Received:2015-10-12 Published:2016-01-13
  • Contact: Jing-Cheng HAO E-mail:jhao@sdu.edu.cn
  • Supported by:
    the National Natural Science Foundation of China(2140102006, 21273134);Shandong Provincial Natural ScienceFoundation, China(ZR2013BQ025)

Abstract:

Rich phase behavior was observed in salt-free cationic/anionic (catanionic) surfactant mixtures of lauric acid (LA) with a nonionic surfactant, tetradecyldimethylamine oxide (C14DMAO), in water. The phase behavior and microstructures of the LA/C14DMAO/H2O system were investigated by freeze-fracture transmission electron microscope (FF-TEM), polarized optical microscope (POM), differential scanning calorimetry (DSC), rheological measurements, and [2]H NMR. A variety of self-assembled microstructures were determined, including micelles (L1 phase), lamellae (Lαl phase), vesicles (Lαν phase) and gels. Using the L1 and Lαl phases as the templates, gold nanoparticles could be produced, as confirmed by transmission electron microscope (TEM) and energy dispersive spectrometer (EDS). Compared with the traditional method of preparing Au nanomaterials in aqueous solutions, this method can avoid the addition of NaBH4 as a reducing agent. The sample solution plays roles as a template and a reductant and the reduction process does not destroy the original self-assembled microstructures in the solution. Hence, by controlling the aggregate structures of the template solution, one can achieve the goal of regulating the morphology of Au nanomaterials, which provides a new path for the preparation of noble metal nanostructured materials with different shapes and structures. The results of the methyl thiazolyl tetrazolium (MTT) assay with HK-2 cells show that, as a gene carrier, spherical Au-nanoparticles prepared in a micellar phase possess the characteristics of higher loading efficiency and lower toxicity than those obtained in traditional surfactant systems, demonstrating potential applications in gene therapy.

Key words: Lauric acid, Tetradecyldimethylamine oxide, Phase behavior, Template, Au nanomaterial

MSC2000: 

  • O648