Acta Phys. -Chim. Sin. ›› 1997, Vol. 13 ›› Issue (03): 247-251.doi: 10.3866/PKU.WHXB19970312

• ARTICLE • Previous Articles     Next Articles

The Ability of Photosensitization and Anti-cancer of ZnPcSP under Different Exciting Wavelength

Huang Jian-Dong,Liu Er-Sheng,Yang Su-Ling,Ouyang Rui-Zhen,Chen Nai-Sheng,Huang Jin-Ling,Huang Zi-Qiang,Sun Jian-Cheng,Xu Jian-Hua   

  1. Department of Chemistry,Institute of Functional Materials,Fuzhou University,Fuzhou 350002|Cancer Pharmacology Research Section,Fujian Medical University,Fuzhou 350004
  • Received:1996-05-21 Revised:1996-12-03 Published:1997-03-15
  • Contact: Huang Jian-Dong

Abstract:

The effect of wavelength of exciting light upon the ability of photogenerating singlet oxygen (1O2) and of killing cancer cells of ZnPcSP were studied. The results show that the effect on the ability of photogenerating 1O2 and the ability of killing cancer cells has the same tendency, i.e., the light of 670nm possesses the best exciting efficency. The result also suggests that type Ⅱreaction of producing 1O2 is probably the main photosensitive type in PDT of ZnPcSP.

Key words: Zinc phthalocyanine, Photodynamic therapy of cancer, Photosensitive reaction, Singlet oxygen