Acta Phys. -Chim. Sin. ›› 1999, Vol. 15 ›› Issue (11): 1005-1010.doi: 10.3866/PKU.WHXB19991110

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Spectroscopic and Electrochemical Studies of Phenylhydrazine-α-cyclodextrin lnclusion Complex and Its Adsorption Behaviors

Gao Zuo-Ning, Li Hu-Lin   

  1. College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000
  • Received:1999-01-22 Revised:1999-04-12 Published:1999-11-15
  • Contact: Li Hu-Lin

Abstract:

Electrochemical and spectral properties of phenylhydrazine hydrochloride (PH) in aqueous solutions in the presence of α-cyclodextrin (α-CD) were investigated. Spectral results indicate that phenylhydrazine hydrochloride can form 1∶1 inclusion complex with α CD in aqueous solutions. The formation constant of the complex, Kf=178 mol-1•dm3,was evaluated by UV spectrometry. It was observed that the light and oxygen sensitivity of the inclusion complex is much lower than that of the uncomplexed PH, this can be used to improve its storage and handling, and also widen its applications in pharmaceutical industry .Furthermore, it was found that its electrochemical oxidability in aqueous solutions can be greatly suppressed in the presence of α-CD.

Key words: Phenylhydrazine, Inclusion complex, α-cyclodextrin, Adsorption