Acta Phys. -Chim. Sin. ›› 1990, Vol. 6 ›› Issue (05): 562-567.doi: 10.3866/PKU.WHXB19900510

• ARTICLE • Previous Articles     Next Articles

Structural Prediction on the Anti-lipolytic Polypeptide of Ginseng

Zhang Fu-Gui; Zhu Min-Hui; Wang Da-Wei; Zhang Jin; Zhang Hong-Ying   

  1. Electronics Institute, Academia Sinica, Beijing; Laboratory of Enzyme Engineering, Jilin University, Changchun
  • Received:1989-01-04 Revised:1990-03-20 Published:1990-10-15
  • Contact: Zhu Min-Hui

Abstract: In this paper, the structure of the anti-lipolytic 14 peptides of Ginseng was studied. Based on the primary structure, the secondary structure was predicted to be mainly a helicity segment which linked a short coil region. We computed the relative conformational energy and the atomic coordinate of Ginseug polypeptide, simulated the optimizing process of conformational energy, obtained the possible energy-minimized conformation by means of molecular mechanics combined with the information from crystallographic database. We also built the corresponding three-dimension model of the Ginseng polypeptide. We also built the corresponding three-dimension model of the Ginseng polypeptide. The stereo structure of the model indicated that the result of the conformation analysis corresponded to the conclusion of the secondary structure prediction.
Ginseng is a renowned and precious medico-botanical which contains many ...