Acta Phys. -Chim. Sin. ›› 2010, Vol. 26 ›› Issue (07): 1847-1851.doi: 10.3866/PKU.WHXB20100612

• COLLOID AND INTERFACE CHEMISTRY • Previous Articles     Next Articles

Interaction between [1,1'-Binaphthalene]-2,2'-diols and a Solid Supported Bilayer Lipid Membrane

AN Shen-Jing, GAN Li-Hua, CHEN Liu-Hua, LIU Ming-Xian, ZHU Da-Zhang, XU Zi-Jie, HAO Zhi-Xian, CHEN Long-Wu   

  1. Department of Chemistry, Tongji University, Shanghai 200092, P. R. China
  • Received:2009-12-01 Revised:2010-03-08 Published:2010-07-02
  • Contact: GAN Li-Hua E-mail:ganlh@tongji.edu.cn

Abstract:

The interaction between [1,1'-binaphthalene]-2,2'-diols (BINOL) and a solid supported bilayer lipid membrane (s-BLM) was studied by cyclic voltammetry and alternating current (AC) impedance measurements. Results indicate that BINOL interacts with s-BLMthrough hydrogen bonding and hydrophobic interaction. The oxidation peak current of the BINOL/s-BLMsystem increases initially and then decreases with an increase in time. This suggests that BINOL gradually destroys the integrity of s-BLM and induces the formation of microchannels within the membrane. The infiltration time of BINOL through the s-BLM decreases as the BINOL concentration increases. With an increase in lecithin and cholesterol content, the membrane resistance of s-BLM increases and the infiltration rate of BINOL through the membrane decreases, which results in a reduction of the infiltration capacity of BINOL towards s-BLM.

Key words: Interaction, Solid supported bilayer lipid membrane, [1,1'-binaphthalene]-2,2'-diols, Infiltration

MSC2000: 

  • O646