Acta Phys. -Chim. Sin. ›› 2012, Vol. 28 ›› Issue (09): 2141-2147.doi: 10.3866/PKU.WHXB201206201

• CATALYSIS AND SURFACE SCIENCE • Previous Articles     Next Articles

Heterogeneously Catalyzed One-Pot Synthesis of N-alkyl anilines from Nitroaromatics by Assembled Pt3Sn/Al2O3 Catalyst

YANG Fang, XU Xiang-Sheng, GU Hui-Zi, CHEN Ao-Ang, YAN Xin-Huan   

  1. State Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014, P. R. China
  • Received:2012-04-06 Revised:2012-06-20 Published:2012-08-02
  • Supported by:

    The project was supported by the National Natural Science Foundation of China (21076197), Natural Science Foundation of Zhejiang Province, China (Y4090440), and Qianjiang Talent Program of Zhejiang Province, China (2010R10038).


N-alkyl anilines were obtained from nitroaromatics by a one-pot method using assembled Pt3Sn/Al2O3 catalyst for heterogeneous in situ hydrogenation in a continuous-flow fixed-bed reactor. At the optimum reaction conditions (503 K, liquid hourly space velocity (LHSV) of 7.5 h-1, 5% (volume fraction) water, 1% (mass fraction) Pt3Sn/Al2O3 catalyst), nitrobenzene conversion was 100%, with a total N-ethyl and N,N-diethyl aniline yield of 98.2%. Moreover, the Pt3Sn/Al2O3 catalyst had a great conjoint effect for all in situ hydrogenation reactions for N-alkylation. High yields of N-alkylation products were obtained in aliphatic alcohol/water systems for 14 selected nitroaromatics.

Key words: N-alkylation, In situ liquid hydrogenation, Nitroaromatic, N-alkyl aniline, Pt-Sn bimetallic catalyst


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