Acta Phys. -Chim. Sin. ›› 2017, Vol. 33 ›› Issue (1): 28-39.doi: 10.3866/PKU.WHXB201609213

• FEATURE ARTICLE • Previous Articles     Next Articles

Applications of Graphitic Nanomaterial's Optical Properties in Biochemical Sensing

Yi-Ting XU1,Long CHEN2,*(),Zhuo CHEN1,*()   

  1. 1 State Key Laboratory of Cheme/Biosensing and Chemometric, Hunan University, Changsha 410006, P. R. China
    2 Faculty of Science and Technology, University of Macau, Macao 999078, P. R. China
  • Received:2016-06-15 Published:2016-12-29
  • Contact: Long CHEN,Zhuo CHEN;
  • Supported by:
    The project was supported by the National Key Basic Research Program of China (973)(2013CB932702);National Natural Science Foundation of China(21522501);and Science and Technology Development Fund of Macao S.A.R, China(FDCT);and Science and Technology Development Fund of Macao S.A.R, China(067/2014/A)


Graphitic nanomaterials, which possess unique optical properties, have attracted significant attention in biochemical sensing. Herein, we summarize and discuss recent progress of such materials as optical probes, photothermal materials and signal transduction substrates for biosensing applications. The most attractive optical property of graphitic nanomaterials is their strong and unique Raman signals. As a Raman probe, these nanomaterials have remarkable applications, especially in detecting complex biological samples, quantitative surface enhanced Raman scattering (SERS) detection and detection under extreme conditions. Besides Raman, the unique intrinsic fluorescence emission of single-walled carbon nanotubes (SWNTs) in the long wavelength and second near-infrared window (NIR-II window, 1000-1700 nm) has facilitated deep-tissue high-resolution fluorescence imaging in vivo. Additionally, graphitic nanomaterials have efficient photothermal conversion capability. Together with the large surface area, graphitic nanomaterials are used in photothermal synergy therapy for cancer treatment. Furthermore, because of their particular physical and chemical properties, graphitic nanomaterials are established as an efficient signal transduction substrate, which can quench an excited chromophore and photosensitizer, showing high selectivity and sensitivity in biosensing and nanomedicine.

Key words: Graphitic nanomaterial, Biochemical sensing, Raman probe, Molecular detection, Photothermal therapy


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