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Acta Physico-Chimica Sinca  2017, Vol. 33 Issue (5): 960-967    DOI: 10.3866/PKU.WHXB201702086
ARTICLE     
Selective Photoelectrochemical Oxidation of Chiral Ibuprofen Enantiomers
Wei-Guo DAI1,Dan-Nong HE1,2,*()
1 National Engineering Research Center for Nanotechnology, Shanghai 200241, P. R. China
2 School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China
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Abstract  

The photoelectrochemical method was combined with the in-situ molecular imprinting technique. Using the chiral ibuprofen enantiomers (S-ibuprofen and R-ibuprofen) as template molecules, S-ibuprofen and R-ibuprofen molecular imprinting sites were constructed on the surface of monocrystalline TiO2 nanorods. The imprinted electrodes were capable of selective recognition and catalytic oxidation of S-ibuprofen and Ribuprofen. The morphology, structure, and composition of the electrode were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Raman spectroscopy. The electron transfer resistance of the electrode surface was studied with electrochemical impedance spectroscopy. The photoelectrochemical recognition and degradation were measured photoelectrochemically using the prepared imprinted electrodes as the working electrode. The TiO2 prepared was a single crystal nanorod array. The imprinted sites were successfully constructed on the surface of TiO2 nanorods and had shape selective adsorption capacities. The selective recognition and selective oxidative degradation of chiral ibuprofen enantiomers on the surface of artificial photoelectrocatalysts were realized for the first time.



Key wordsIbuprofen      Monocrystalline TiO2      Photoelectrochemical recognition      Shape selective adsorption      Selective oxidative degradation     
Received: 12 December 2016      Published: 08 February 2017
MSC2000:  O649  
Fund:  the International Science and Technology Cooperation Program of China(2015CB931902)
Corresponding Authors: Dan-Nong HE     E-mail: hdn_nercn@163.com
Cite this article:

Wei-Guo DAI,Dan-Nong HE. Selective Photoelectrochemical Oxidation of Chiral Ibuprofen Enantiomers. Acta Physico-Chimica Sinca, 2017, 33(5): 960-967.

URL:

http://www.whxb.pku.edu.cn/10.3866/PKU.WHXB201702086     OR     http://www.whxb.pku.edu.cn/Y2017/V33/I5/960

Fig 1 Structural formula of S-ibuprofen (left) and R-ibuprofen (right)
Fig 2 Scanning electron microscopy (SEM), transmission electron microscopy (TEM), selected area electron diffraction (SAED) and high resolution transmission electron microscopy (HRTEM) of TiO2 (A), S-ibuprofen-TiO2 (B) and R-ibuprofen-TiO2 (C)
Fig 3 XRD of TiO2 (a), S-ibuprofen-TiO2 (b) and R-ibuprofen-TiO2 (c)
Fig 4 Raman spectra of TiO2 (a), S-ibuprofen-TiO2 (b) and R-ibuprofen-TiO2 (c)
Electrode Iblank/(mA?cm-2) IS/(mA?cm-2) IR/(mA?cm-2) SPEC
TiO21.772.242.281.09
S-ibuprofen-TiO21.713.812.263.80
R-ibuprofen-TiO21.712.324.003.73
Table 1 Photoelectrochemistry response of ibuprofen enantiomers on different electrodes
Fig 5 Electron transfer resistance on the surface of different electrodes (a) TiO2; (b) S-ibuprofen-TiO2; (c) S-ibuprofen-TiO2 (with template)
Fig 6 Photoelectrocatalytic degradation of S-ibuprofen and R-ibuprofen on the S-ibuprofen-TiO2 electrode (A, B) and R-ibuprofen-TiO2 electrode (C, D)
Fig 7 Absorption of S-ibuprofen and R-ibuprofen by different electrodes
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