To evaluate the thermal safety of 2,2,2-trinitroethyl-*N*-nitromethyl amine (TNMA), basic data, including specific heat capacity (*C*_{p}) and thermal conductivity (*λ*), were estimated using empirical formulae. The standard enthalpy of formation of TNMA, Δ_{f}*H*_{m}^{θ}(TNMA, s, 298.15 K), was calculated by an additive method of contributing bond energy to heat of formation *Q*_{f}, and the standard combustion enthalpy Δ_{c}*H*_{m}^{θ}(TNMA, s, 298.15 K) and standard combustion energy Δ*U*_{m}^{θ} (TNMA, s, 298.15 K) and standard combustion energy Δ*U*_{m}^{θ} (TNMA, s, 298.15 K) were calculated by thermodynamic formulae. The detonation velocity, detonation pressure, and heat of detonation were estimated using the Kamlet-Jacobs equation. The heat of decomposition reaction (*Q*_{d}) of TNMA was estimated by an empirical formula, and the thermal behavior of TNMA was studied by differential scanning calorimetry (DSC). The kinetic parameters of the exothermic decomposition reaction of TNMA were obtained from analysis of DSC curves and standard volume of gas evolved (VH) vs time (t) curves determined using a highly sensitive Bourdon glass membrane manometer. The parameters used to evaluate the thermal safety of TNMA, such as the self-accelerating decomposition temperature (*T*_{SADT}), critical temperature of thermal explosion (*T*_{be} and *T*_{bp}), adiabatic time-to-explosion (*t*_{TIad}), 50% drop height (*H*_{50}) of impact sensitivity, critical temperature of hot-spot initiation (*T*_{cr}), thermal sensitivity probability density function *S*(*T*) for infinite plate-like, infinite cylindrical and spheroidal TNMAwith half-thickness and radius of 1 m at 300 K, peak temperature corresponding to the maximum value of the *S*(*T*) *vs T* curve (*T _{S}*