咪唑修饰萘酰亚胺与DNA的作用及其细胞毒性

高云燕,蔡温姣,欧植泽,马拖拖,倚娜,李志远

DNA Interactions and Cytotoxicity of Imidazole-Modified Naphthalimides

Yunyan GAO,Wenjiao CAI,Zhize OU,Tuotuo MA,Na YI,Zhiyuan LI

图8 A549细胞用化合物(a) 3，(d) 4b，及DAPI (b，e)孵育4.0 h后的荧光成像。(c)图(a)和(b)的叠加图；(f)图(d)和(e)的叠加图

Fig 8 Fluorescence images of A549 cells incubated with (a) 3, (d) 4b, and DAPI (b, e) for 4.0 h. (c) merged image of (a) and (b); (f) merged image of (d) and (e). [3] = [4b] = 10 μmol·L−1, [DAPI] = 5 μmol·L−1.