高效医学传感钙钛矿材料研究进展

杨帅, 徐瑜歆, 郝子坤, 秦胜建, 张润鹏, 韩钰, 杜利伟, 朱紫洢, 杜安宁, 陈欣, 吴昊, 乔冰冰, 李坚, 王艺, 孙昺晨, 闫融融, 赵晋津

Recent Advances in High-Efficiency Perovskite for Medical Sensors

Shuai Yang, Yuxin Xu, Zikun Hao, Shengjian Qin, Runpeng Zhang, Yu Han, Liwei Du, Ziyi Zhu, Anning Du, Xin Chen, Hao Wu, Bingbing Qiao, Jian Li, Yi Wang, Bingchen Sun, Rongrong Yan, Jinjin Zhao

图4 钙钛矿电催化医学传感器的工作原理和器件性能。(a)钙钛矿电催化医学传感器的检测原理；(b) GdTiO₃-石墨烯修饰的玻碳电极(GCE)对多巴胺和对乙酰氨基酚的检测原理示意图¹⁰⁵；(c)在不同葡萄糖浓度下NdNiO₃/GCE的伏安特性曲线，插图：氧化峰峰值电流随葡萄糖浓度的变化⁶⁸；(d)不同多巴胺(DA)浓度下，GdTiO₃-石墨烯修饰的GCE的差分脉冲伏安特性曲线¹⁰⁵；(e) LaMnO₃的X射线光电子能谱中的Mn 2p谱，显示出Mn³⁺和Mn⁴⁺在LaMnO₃中共存²²；(f)不同的DA浓度、尿酸浓度和对乙酰氨基酚浓度下，LaNi_0.8Co_0.2O₃/碳糊电极(CPE)的伏安特性曲线²⁸；(g)不同H₂O₂浓度下，LaNi_0.6Co_0.4O₃/CPE的电流–时间响应⁶⁷；(h) NdNiO₃/全氟磺酸膜异质结谷氨酸传感器的器件外观、沿老鼠脑部的插入路径和刺激小鼠大脑的实验环境²⁷

Fig 4 Operation mechanisms and device performances of perovskite electrocatalytic medical sensors. (a) Sensing mechanism of perovskite electrocatalytic medical sensors. (b) The operation mechanism of GdTiO₃ graphene modified glassy carbon electrode (GCE) for sensing dopamine and acetaminophen ¹⁰⁵. (c) Voltage–ampere curves of NdNiO₃/GCE under different glucose concentrations, and the inset is the variation of oxidation peak current with glucose concentrations ⁶⁸. (d) Differential pulse voltammetry curves of GdTiO₃-graphene modified GCE at different dopamine (DA) concentrations ¹⁰⁵. (e) The Mn 2p spectrum in the X-ray photoelectron spectroscopy of LaMnO₃, which shows that Mn³⁺and Mn⁴⁺ coexist ²². (f) Voltage–ampere curves of LaNi_0.8Co_0.2O₃/carbon paste electrode (CPE) at different DA concentrations, uric acid concentrations and acetaminophen concentrations²⁸. (g) Current–time response of LaNi_0.6Co_0.4O₃/CPE at different H₂O₂ concentrations ⁶⁷. (h) The device appearance, device insertion path along mouse brain and experimental environment for stimulating mouse brain of the NdNiO₃/Nafion heterojunction glutamate sensor ²⁷.
(b) Adapted from Elsevier publisher; (c) Adapted from Royal Society of Chemistry publisher^; (d) Adapted from Elsevier publisher; (e) Adapted from Elsevier publisher; (f) Adapted from Elsevier publisher; (g) Adapted from Elsevier publisher; (h) Adapted from Elsevier publisher.