物理化学学报 >> 1997, Vol. 13 >> Issue (05): 389-394.doi: 10.3866/PKU.WHXB19970502

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亚相pH对气水界面上VE/DPPC单分子膜的影响

莫凤奎,朱治方   

  1. 沈阳药科大学基础部，沈阳 110015
  • 收稿日期:1996-07-07 修回日期:1996-12-27 发布日期:1997-05-15
  • 通讯作者:

Affect of Subphase pH on the Behavior of the Monolayers at the Air/Water Interface for Vitamin E and Dipalmitoylphosphatidylcholine

Mo Feng-Kui,Zhu Zhi-Fang   

  1. Department of Basic Courses,Shenyang Pharmaceutical University,Shenyang 110015
  • Received:1996-07-07 Revised:1996-12-27 Published:1997-05-15
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摘要：

通过表面压-分子面积等温线（π－A线）的测定，考察了亚相pH对气水界面上的维生素E（VE）／二棕榈酰基磷脂酰胆碱（DPPC）单分子膜的影响. 亚相pH降低不改变DPPC单分子膜的崩裂压， 但使VE单分子膜的崩裂压明显增大；不改变VE单分子膜的平均分子面积，但使DPPC单分子膜凝缩. 低表面压下，VE对DPPC单分子膜的膨胀作用在纯水上很小，在pH为1的亚相上则很明显. 这提示在低pH的亚相上，VE／DPPC单分子股中的极性头基间的相互作用对膜性质有着重要的影响.

关键词: 维生素E(VE), 二棕榈酰基磷脂酰胆碱(DPPC), 单分子膜, 亚相pH

Abstract:

 The affect of subphase pH on the monolayers at air/water interphase for vitamin E and dipalmitoylphosphatidylcholine was investigated by determining the surface pressure-area isothermis. Decrease in subphase pH didn't change the collapse pressure of monolayer for DPPC,but led to obvious increase in that for VE, it also didn't change the area per molecule of monolayer for VE, but caused DPPC monolayer to be condensed. At lower surface pressure, the action of VE to the expansion of DPPC monolayer was small on pure water, but large on the subphase of pH=1. It suggests that interactions between the polar head groups may play an important role in the behavior of the VE/DPPC monolayers on the subphase of lower pH.

Key words: Vitamin E, Diphlmitoylphosphatidylcholine, Monolayer, pH of subphase