Acta Phys. -Chim. Sin. ›› 2010, Vol. 26 ›› Issue (08): 2057-2060.doi: 10.3866/PKU.WHXB20100837

• COMMUNICATION • Previous Articles     Next Articles

Electrochemical Construction and Biological Performance of Micropatterned CaP Films

HUANG Yong-Xia, LAI Yue-Kun, LIN, Long-Xiang, SUN Lan, LIN Chang-Jian   

  1. Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian Province, P. R. China
  • Received:2010-03-29 Revised:2010-05-20 Published:2010-07-23
  • Contact: SUN Lan, LIN Chang-Jian;
  • Supported by:

    The project was supported by the Major International Collaborative Research Projects of the National Natural Science Foundation of China (20620130427), National Natural Science Foundation of China (20773100), National Key Basic Research Program of China (973) (2007CB935603) and International Scientific and Technological Cooperation Projects of the Ministry of Science and Technology of China (2007DFC40440).


Based on surface molecule self-assembly and photocatalytic lithography techniques, superhydrophilic/superhydrophobic micropatterns were fabricated on TiO2 films. Micropatterned calcium phosphate (CaP) films were successfully fabricated by the as-prepared superhydrophilic/superhydrophobic template combined with the electrochemical deposition method. Scanning electron microscopy (SEM) and electron probe microanalysis (EPMA) indicated that micropatterned CaP films with a high spatial resolution could be constructed using the superhydrophilic/superhydrophobic micropatterns as templates. In vitro MG-63 cell tests of the micropatterned CaP films showed that the cells selectively adhered to the tiny CaP film units, which is promising for the control of the adherent growth of the cells on the tiny units and to achieve a high throughput evaluation of the cell behavior.

Key words: Titania, Superhydrophilic/superhydrophobic, CaP film, Micropattern, Biological performance