物理化学学报 >> 2002, Vol. 18 >> Issue (09): 855-864.doi: 10.3866/PKU.WHXB20020919

综述 上一篇    

硅表面有机单层膜 :微印章、微加工与微阵列

朱晓阳   

  1. Department of Chemistry, University of Minnesota Minneapolis, MN 55455 USA
  • 收稿日期:2002-03-20 修回日期:1900-01-01 发布日期:2002-09-15
  • 通讯作者: 朱晓阳 E-mail:zhu@chem.umn.edu

Organic Monolayers on Silicon:Microprinting, Micromachines, and Microarrrays

Zhu Xiao-Yang   

  1. Department of Chemistry, University of Minnesota Minneapolis, MN 55455,USA
  • Received:2002-03-20 Revised:1900-01-01 Published:2002-09-15
  • Contact: Zhu Xiao-Yang E-mail:zhu@chem.umn.edu

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摘要： 总结了作者的实验室在将有机物结合到硅表面方面的研究进展.发现并发展了将有机单层膜组装到硅、氧化硅和相关材料表面的新方法.这些方法简单、可重复，并可得到物理、化学性能良好的致密单层膜.这些单层膜在许多方面有令人鼓舞的应用，包括（a）应用于软印刷术，特别是微接触印章法; （b）用作硅的微加工（微机电系统，MEMS）的单层膜润滑剂; （c）用作DNA和蛋白质微阵列功能分子固定的基底.

关键词: 硅表面, 自组装单层膜, 微接触印章法, 微机电系统（MEMS）, DNA芯片, 蛋白质芯片

Abstract: This account summarizes recent research in my laboratory on the integration of organic functionalities to silicon surfaces. We have discovered and developed novel, two-step strategies for the assembly of organic monolayers on silicon, silica, and related materials. These methods are simple and reproducible and lead to close packed monolayers with excellent physical/chemical properties. Exciting applications of these monolayers include (a) resists in soft-lithography, particularly micro-contact printing; (b) monolayer lubricant in silicon based micromachines, also called micro electromechanic systems (MEMS); and (c) molecular basis for the immobilization of DNA and protein molecules in microarrays.

Key words: Silicon surface, Self-assembled monolayer, Micro contact printing, MEMS (Microelectromechanical systems), DNA chip, Protein chip