物理化学学报 >> 2007, Vol. 23 >> Issue (10): 1537-1542.doi: 10.3866/PKU.WHXB20071010

研究论文 上一篇    下一篇

负载金属催化剂Ir(γ-Al2O3)对阿维菌素选择加氢反应研究

杨鹏; 樊光银; 马晓艳; 李瑞祥; 李贤均   

  1. 四川大学化学学院,教育部绿色化学与技术重点实验室, 成都 610064
  • 收稿日期:2007-05-07 修回日期:2007-06-12 发布日期:2007-10-01
  • 通讯作者: 李瑞祥 E-mail:sculiruixiang@163.com

Study on Selective Hydrogenation of Avermectin to Ivermectin over Ir/γ-Al2O3

YANG Peng; FAN Guang-Yin MA Xiao-Yan; LI Rui-Xiang; LI Xian-Jun   

  1. Key Laboratory of Green Chemistry and Technology of the Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China
  • Received:2007-05-07 Revised:2007-06-12 Published:2007-10-01
  • Contact: LI Rui-Xiang E-mail:sculiruixiang@163.com

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摘要： 分别采用氢气、NaBH4、醇水混合溶剂还原, PVP(聚乙烯吡咯烷酮)保护和微乳液法制备了γ-Al2O3负载的Ir金属催化剂, 通过XPS、XRD、TEM对催化剂的结构进行了表征, 考察了催化剂对阿维菌素选择加氢制备伊维菌素的性能, 探讨了催化剂制备方法对催化剂活性和选择性的影响. 实验结果表明, 在不同金属催化剂Ru/γ-Al2O3、Pd/γ-Al2O3、Pt/γ-Al2O3、Ir/γ-Al2O3中, Ir/γ-Al2O3的活性和选择性最好. 用PVP保护的Ir/γ-Al2O3, 其催化活性和选择性比没有PVP保护的催化剂有显著提高; 采用微乳液法制备的Ir/γ-Al2O3催化剂显示出最好的活性, 但反应选择性比PVP保护的催化剂差.

关键词: 负载催化剂, 铱, 阿维菌素, 伊维菌素, 选择加氢

Abstract: Catalysts Ir/γ-Al2O3 were prepared by impregnating γ-Al2O3 with an aqueous solution or microemulsion solution ofH2IrCl6. The catalystswere characterized by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and transmission electron microscope (TEM). The catalytic performance of the supportediridiumcatalysts for the selective hydrogenation of avermectin to ivermectin was investigated. Compared with active carbon (AC), α-Al2O3, and TiO2, γ-Al2O3 is a better support in this system. Among Ir, Ru, Pd, and Pt supported on γ-Al2O3, the catalyst Ir/γ-Al2O3 showed the best catalytic activity and selectivity to ivermectin. Ir/γ-Al2O3 prepared by means of microemulsion solution showed the best catalytic activity, but the catalytic selectivity to ivermectin was lower that over Ir/γ-Al2O3 modified with PVP (polyvinylpyrrolidone), which exhibited excellent activity as well as good selectivity.

Key words: Supported catalyst, Iridium, Avermectin, Ivermectin, Selective hydrogenation