Abstract: The effects of cephanone on the surface activity and aggregation behavior of Triton X-100 molecule were studied by the methods of surface tension and fluorescence, respectively. The binding constant between cephanone and Triton X-100 micelles was determined by the method of steady state fluorescence. The location of cephanone in Triton X-100 micelles was investigated through nuclear magnetic spectroscopy (NMR). The results showed that the surface activity of Triton X-100 decreased with the increase of cephanone concentration. With the increase of Triton X-100 concentration, the binding constant between cephanone and Triton X-100 micelles decreased, but the distribution coefficient of cephanone between Triton X-100 micelles and water continuous phase kept being invariable. The results of ¹H-NMR showed that cephanone was located around the polar group of Triton X-100 micelle.

Key words: Cephanone, Triton X-100, Surface activity, Aggregation number, Binding constant, Distribution coefficient