单分子电导测量技术及其影响因素

doi:10.3866/PKU.WHXB201909043

Abstract

Abstract:

Molecular electronics is an important field for the application of nanotechnologies with an ultimate goal of building functional devices using single molecules or molecular arrays to realize the same functionality as macroscopic devices. To attain this goal, reliable techniques for measuring and manipulating electron transfer processes through single molecules are essential. There are various techniques and many environmental factors influencing single-molecule electronic conductance measurements. In this review, we first provide a detailed introduction and classification of the current well-accepted techniques in this field for measuring single-molecule conductance. All available techniques are summarized into two categories: the fixed junction technique and break junction technique. The break junction technique involves repeatedly forming and breaking molecular junctions by mechanically controlling a pair of electrodes moving into and out of contact in the presence of target molecules. Single-molecule conductance can be determined from the conductance plateaus that appear in typical conductance decay traces when molecules bind two electrodes during their separation process. In contrast, the fixed junction technique is to fix the distance between a pair of electrodes and measure the conductance fluctuations when a single molecule binds the two electrodes stochastically. Both techniques comprise different application methods and have been employed preferentially by different groups. Specific features of both techniques and their intrinsic advantages are compared and summarized in Section 4.

Next, we systematically summarize the factors affecting the molecular conductance during the course of measurements, which are the focus of the current academic community in the field. As shown in the middle of the image above, the electrode, anchoring group, and target molecule are the three key elements in constructing a single-molecule junction. The contact geometry between the molecule and the electrode and the associated coupling strength can profoundly affect the conductance characteristics of single molecules. The properties of anchoring groups can determine whether a molecule is primarily transported by electrons or holes. A good selection of electrode materials can improve the yield of single-molecule junctions and facilitate strong electronic couplings with the target molecules. The conductance characteristics of saturated and conjugated molecules are quite different due to their diverse band gaps. Moreover, various substituents can be modified onto the backbone of the molecules, which can raise or lower the energy level of the frontier orbitals of molecules to different degrees, thereby affecting the conductance properties of target molecules. In addition to these factors for the key elements, the investigated molecules can be measured in a variety of environments, including organic solvents, high vacuum, aqueous solution, ionic liquids, or the atmosphere, and the work function of the metal contact may change in different environments. The change in work function can change the gap between the electrode Fermi energy and the frontier orbital of a target molecule, influencing the measured conductance. Additionally, both the electrical field orientation and the bias values applied have a significant effect on the molecular structures and thus their conductance characteristics. Temperature can also affect the charge transport when hopping dominates the transport mechanism. Meanwhile, pH affects the interactions between H⁺/OH^- and the anchoring groups, which indirectly induces a change in the tunneling barrier.

In this review, the influencing factors are comprehensively illustrated from two perspectives: internal factors (anchoring group, electrode, and target molecule) and external factors (voltage, temperature, solvent, pH value, and others). In addition, new approaches for modulating the molecular conductance (modulation of energy levels, light or heat stimulation, and others) that have been developed in recent years are reviewed, and investigations of chemical reactions at the single-molecule level using these methods are highlighted. Finally, the potential applications of these techniques and correlated modulating approaches are summarized and a prospective is provided for the field of single-molecule electronics.

Key words: Single molecule conductance measurement, Fixed junction, Break junction, Anchoring group, Influencing factor of conductance

Pengkun Cheng, Yunchuan Li, Shuai Chang. Techniques and Influencing Factors for Single Molecule Electronic Conductance Measurements[J]. Acta Physico-Chimica Sinica 2020, 36(11), 1909043. doi: 10.3866/PKU.WHXB201909043

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References 134

1	Feynman R. P Calif. Inst. Technol. J. Eng. Sci. 1960, 4, 23.
2	Aviram A. ; Ratner M. A Chem. Phys. Lett. 1974, 29, 277. doi: 10.1016/0009-2614(74)85031-1
3	Qin L. ; Park S. ; Huang L. ; Mirkin C. A Science 2005, 309, 113. doi: 10.1126/science.1112666
4	Chen X. ; Yeganeh S. ; Qin L. ; Li S. ; Xue C. ; Braunschweig A. B. ; Schatz G. C. ; Ratner M. A. ; Mirkin C. A Nano Lett. 2009, 9, 3974. doi: 10.1021/nl9018726
5	Klein D. L. ; McEuen P. L. ; Katari J. E. B. ; Roth R. ; Alivisatos A. P Appl. Phys. Lett. 1996, 68, 2574. doi: 10.1063/1.116188
6	Park H. ; Lim A. K. L. ; Alivisatos A. P Appl. Phys. Lett. 1999, 75, 301. doi: 10.1063/1.124354
7	Reed M. A. ; Zhou C. ; Muller C. J. ; Burgin T. P. ; Tour J. M Science 1997, 278, 252. doi: 10.1126/science.278.5336.252
8	Zhang Y. P. ; Chen L. C. ; Zhang Z. Q. ; Cao J. J. ; Tang C. ; Liu J. ; Duan L. L. ; Huo Y. ; Shao X. ; Hong W. ; et al J. Am. Chem. Soc. 2018, 140, 6531. doi: 10.1021/jacs.8b02825
9	Wold D. J. ; Frisbie C. D J. Am. Chem. Soc. 2000, 122, 2970. doi: 10.1021/ja994468h
10	Cui X. D. ; Primak A. ; Zarate X. ; Tomfohr J. ; Sankey O. F. ; Moore A. L. ; Moore T. A. ; Gust D. ; Harris G. ; Lindsay S. M Science 2001, 294, 571. doi: 10.1126/science.1064354
11	Xu B. ; Xiao X. ; Tao N. J J. Am. Chem. Soc. 2003, 125, 16164. doi: 10.1021/ja038949j
12	Xu B. ; Tao N. J Science 2003, 301, 1221. doi: 10.1126/science.1087481
13	He J. ; Sankey O. ; Lee M. ; Tao N. ; Li X. ; Lindsay S Faraday Discuss. 2006, 131, 145. doi: 10.1039/b508434m
14	Haiss W. ; Nichols R. J. ; van Zalinge H. ; Higgins S. J. ; Bethell D. ; Schiffrin D. J Phys. Chem. Chem. Phys. 2004, 6, 4330. doi: 10.1039/B404929B
15	Pla-Vilanova P. ; Aragones A. C. ; Ciampi S. ; Sanz F. ; Darwish N. ; Diez-Perez I Nanotechnology 2015, 26, 381001. doi: 10.1088/0957-4484/26/38/381001
16	Haiss W. ; van Zalinge H. ; Higgins S. J. ; Bethell D. ; Höbenreich H. ; Schiffrin D. J. ; Nichols R. J J. Am. Chem. Soc. 2003, 125, 15294. doi: 10.1021/ja038214e
17	Haiss W. ; Wang C. ; Grace I. ; Batsanov A. S. ; Schiffrin D. J. ; Higgins S. J. ; Bryce M. R. ; Lambert C. J. ; Nichols R. J Nat. Mater. 2006, 5 (12), 995. doi: 10.1038/nmat1781
18	Liang X. ; Chou S. Y Nano Lett. 2008, 8, 1472. doi: 10.1021/nl080473k
19	Guo X. ; Small J. P. ; Klare J. E. ; Wang Y. ; Purewal M. S. ; Tam I. W. ; Hong B. H. ; Caldwell R. ; Huang L. ; O'Brien S Science 2006, 311, 356. doi: 10.1126/science.1120986
20	Prins F. ; Barreiro A. ; Ruitenberg J. W. ; Seldenthuis J. S. ; Aliaga-Alcalde N. ; Vandersypen L. M. K. ; van der Zant H. S. J Nano Lett. 2011, 11, 4607. doi: 10.1021/nl202065x
21	Brandl T. ; El Abbassi M. ; Stefani D. ; Frisenda R. ; Harzmann G. D. ; van der Zant H. S. J. ; Mayor M Eur. J. Org. Chem. 2019, 2019, 5334. doi: 10.1002/ejoc.201900432
22	Lumbroso O. S. ; Simine L. ; Nitzan A. ; Segal D. ; Tal O Nature 2018, 562, 240. doi: 10.1038/s41586-018-0592-2
23	Su T. A. ; Neupane M. ; Steigerwald M. L. ; Venkataraman L. ; Nuckolls C Nat. Rev. Mater. 2016, 1, 2058. doi: 10.1038/natrevmats.2016.2
24	Xiang D. ; Wang X. ; Jia C. ; Lee T. ; Guo X Chem. Rev. 2016, 116, 4318. doi: 10.1021/acs.chemrev.5b00680
25	Yu P. ; Feng A. ; Zhao S. ; Wei J. ; Yang Y. ; Shi J. ; Hong W Acta Phys. -Chim. Sin. 2019, 35, 829.
	余培锴; 冯安妮; 赵世强; 魏珺颖; 杨扬; 师佳; 洪文晶. 物理化学学报, 2019, 35, 829. doi: 10.3866/PKU.WHXB201811027
26	Muller C. J. ; van Ruitenbeek J. M. ; de Jongh L. J Phys. Rev. Lett. 1992, 69, 140. doi: 10.1103/PhysRevLett.69.140
27	Huang C. ; Rudnev A. V. ; Hong W. ; Wandlowski T Chem. Soc. Rev. 2015, 44, 889. doi: 10.1039/c4cs00242c
28	Konishi T. ; Kiguchi M. ; Takase M. ; Nagasawa F. ; Nabika H. ; Ikeda K. ; Uosaki K. ; Ueno K. ; Misawa H. ; Murakoshi K J. Am. Chem. Soc. 2013, 135, 1009. doi: 10.1021/ja307821u
29	Xiang D. ; Jeong H. ; Lee T. ; Mayer D Adv. Mater. 2013, 25, 4845. doi: 10.1002/adma.201301589
30	Wang L. ; Wang L. ; Zhang L. ; Xiang D Top. Curr. Chem. (Cham) 2017, 375, 61. doi: 10.1007/s41061-017-0149-0
31	Venkataraman L. ; Klare J. E. ; Tam I. W. ; Nuckolls C. ; Hybertsen M. S. ; Steigerwarld M. L Nano Lett. 2006, 6, 458. doi: 10.1021/nl052373+
32	Park Y. S. ; Whalley A. C. ; Kamenetska M. ; Steigerwald M. L. ; Hybertsen M. S. ; Nuckolls C. ; Venkataraman L J. Am. Chem. Soc. 2007, 129, 15768. doi: 10.1021/ja0773857
33	Hong W. ; Li H. ; Liu S. X. ; Fu Y. ; Li J. ; Kaliginedi V. ; Decurtins S. ; Wandlowski T J. Am. Chem. Soc. 2012, 134, 19425. doi: 10.1021/ja307544w
34	Hong W. ; Manrique D. Z. ; Moreno-Garcia P. ; Gulcur M. ; Mishchenko A. ; Lambert C. J. ; Bryce M. R. ; Wandlowski T J. Am. Chem. Soc. 2012, 134, 2292. doi: 10.1021/ja209844r
35	Li Z. ; Smeu M. ; Ratner M. A. ; Borguet E J. Phys. Chem. C 2013, 117, 14890. doi: 10.1021/jp309871d
36	Ponce J. ; Arroyo C. R. ; Tatay S. ; Frisenda R. ; Gavina P. ; Aravena D. ; Ruiz E. ; van der Zant H. S. ; Coronado E J. Am. Chem. Soc. 2014, 136, 8314. doi: 10.1021/ja5012417
37	Xiao B. ; Liang F. ; Liu S. ; Im J. ; Li Y. ; Liu J. ; Zhang B. ; Zhou J. ; He J. ; Chang S Nanotechnology 2018, 29, 365501. doi: 10.1088/1361-6528/aacb63
38	Chen F. ; Li X. ; Hihath J. ; Huang Z. ; Tao N J. Am. Chem. Soc. 2006, 128, 15874. doi: 10.1021/ja065864k
39	Quek S. Y. ; Venkataraman L. ; Choi H. J. ; Louie S. G. ; Hybertsen M. S. ; Neaton J. B Nano Lett. 2007, 7, 3477. doi: 10.1021/nl072058i
40	Dell'Angela M. ; Kladnik G. ; Cossaro A. ; Verdini A. ; Kamenetska M. ; Tamblyn I. ; Quek S. Y. ; Neaton J. B. ; Cvetko D. ; Morgante A Nano Lett. 2010, 10, 2470. doi: 10.1021/nl100817h
41	Venkataraman L. ; Park Y. S. ; Whalley A. C. ; Nuckolls C. ; Hybertsen M. S. ; Steigerwald M. L Nano Lett. 2007, 7, 502. doi: 10.1021/nl062923j
42	Mishchenko A. ; Zotti L. A. ; Vonlanthen D. ; Bürkle M. ; Pauly F. ; Cuevas J. C. ; Mayor M. ; Wandlowski T J. Am. Chem. Soc. 2011, 133, 184. doi: 10.1021/ja107340t
43	Quek S. Y. ; Kamenetska M. ; Steigerwald M. L. ; Choi H. J. ; Louie S. G. ; Hybertsen M. S. ; Neaton J. B. ; Venkataraman L Nat. Nanotechnol. 2009, 4, 230. doi: 10.1038/nnano.2009.10
44	Dadosh T. ; Gordin Y. ; Krahne R. ; Khivrich I. ; Mahalu D. ; Frydman V. ; Sperling J. ; Yacoby A. ; Bar-Joseph I Nature 2005, 436, 677. doi: 10.1038/nature03898
45	Martin C. A. ; Ding D. ; Sorensen J. K. ; Bjornholm T. ; van Ruitenbeek J. M. ; van der Zant H. S J. Am. Chem. Soc. 2008, 130, 13198. doi: 10.1021/ja804699a
46	Schneebeli S. T. ; Kamenetska M. ; Cheng Z. ; Skouta R. ; Friesner R. A. ; Venkataraman L. ; Breslow R J. Am. Chem. Soc. 2011, 133, 2136. doi: 10.1021/ja111320n
47	Kiguchi M. ; Tal O. ; Wohlthat S. ; Pauly F. ; Krieger M. ; Djukic D. ; Cuevas J. C. ; van Ruitenbeek J. M Phys. Rev. Lett. 2008, 101, 046801. doi: 10.1103/PhysRevLett.101.046801
48	Kaneko S. ; Nakazumi T. ; Kiguchi M J. Phys. Chem. Lett. 2010, 1, 3520. doi: 10.1021/jz101506u
49	Li Y. ; Xiao B. ; Chen R. ; Chen H. ; Dong J. ; Liu Y. ; Chang S Chem. Commun. 2019, 55, 8325. doi: 10.1039/c9cc02998b
50	Cheng Z. L. ; Skouta R. ; Vazquez H. ; Widawsky J. R. ; Schneebeli S. ; Chen W. ; Hybertsen M. S. ; Breslow R. ; Venkataraman L Nat. Nanotechnol. 2011, 6, 353. doi: 10.1038/nnano.2011.66
51	Chen W. ; Widawsky J. R. ; Vazquez H. ; Schneebeli S. T. ; Hybertsen M. S. ; Breslow R. ; Venkataraman L J. Am. Chem. Soc. 2011, 133, 17160. doi: 10.1021/ja208020j
52	Hines T. ; Diez-Perez I. ; Nakamura H. ; Shimazaki T. ; Asai Y. ; Tao N J. Am. Chem. Soc. 2013, 135, 3319. doi: 10.1021/ja3106434
53	Ko C. H. ; Huang M. J. ; Fu M. D. ; Chen C. H J. Am. Chem. Soc. 2010, 132, 756. doi: 10.1021/ja9084012
54	Zhou X. S. ; Liang J. H. ; Chen Z. B. ; Mao B. W Electrochem. Commun. 2011, 13, 407. doi: 10.1016/j.elecom.2011.02.005
55	Peng Z. L. ; Chen Z. B. ; Zhou X. Y. ; Sun Y. Y. ; Liang J. H. ; Niu Z. J. ; Zhou X. S. ; Mao B. W J. Phys. Chem. C 2012, 116, 21699. doi: 10.1021/jp3069046
56	Wang Y. H. ; Zhou X. Y. ; Sun Y. Y. ; Han D. ; Zheng J. F. ; Niu Z. J. ; Zhou X. S Electrochim. Acta 2014, 123, 205. doi: 10.1016/j.electacta.2014.01.041
57	He C. ; Zhang Q. ; Fan Y. ; Zhao C. ; Zhao C. ; Ye J. ; Dappe Y. ; Nichols R. ; Yang L ChemPhysChem 2019, 20, 1830. doi: 10.1002/cphc.201900424
58	Zhou X. S. ; Wei Y. M. ; Liu L. ; Chen Z. B. ; Tang J. ; Mao B. W J. Am. Chem. Soc. 2008, 130, 13228. doi: 10.1021/ja8055276
59	Zhou C. ; Li X. ; Gong Z. ; Jia C. ; Lin Y. ; Gu C. ; He G. ; Zhong Y. ; Yang J. ; Guo X Nat. Commun. 2018, 9, 807. doi: 10.1038/s41467-018-03203-1
60	Gu C. ; Hu C. ; Wei Y. ; Lin D. ; Jia C. ; Li M. ; Su D. ; Guan J. ; Xia A. ; Xie L Nano Lett. 2018, 18, 4156. doi: 10.1021/acs.nanolett.8b00949
61	Sarwat S. G. ; Gehring P. ; Rodriguez Hernandez G. ; Warner J. H. ; Briggs G. A. D. ; Mol J. A. ; Bhaskaran H Nano Lett. 2017, 17, 3688. doi: 10.1021/acs.nanolett.7b00909
62	Bellunato A. ; Vrbica S. D. ; Sabater C. ; de Vos E. W. ; Fermin R. ; Kanneworff K. N. ; Galli F. ; van Ruitenbeek J. M. ; Schneider G. F Nano Lett. 2018, 18, 2505. doi: 10.1021/acs.nanolett.8b00171
63	Peiris C. R. ; Vogel Y. ; Le Brun A. P. C. ; Aragonès A. ; Coote M. L. ; Díez-Pérez I. ; Ciampi S. ; Darwish N J. Am. Chem. Soc. 2019, 141, 14788. doi: 10.1021/jacs.9b07125
64	Caneva S. ; Gehring P. ; Garcia-Suarez V. M. ; Garcia-Fuente A. ; Stefani D. ; Olavarria-Contreras I. J. ; Ferrer J. ; Dekker C. ; van der Zant H. S. J Nat. Nanotechnol. 2018, 13, 1126. doi: 10.1038/s41565-018-0258-0
65	Xiang L. ; Hines T. ; Palma J. L. ; Lu X. ; Mujica V. ; Ratner M. A. ; Zhou G. ; Tao N J. Am. Chem. Soc. 2016, 138, 679. doi: 10.1021/jacs.5b11605
66	Nitzan A Annu. Rev. Phys. Chem. 2001, 52, 681. doi: 10.1146/annurev.physchem.52.1.681
67	Nitzan A J. Phys. Chem. A 2001, 105, 2677. doi: 10.1021/jp003884h
68	Ie Y. ; Okamoto Y. ; Inoue T. ; Tone S. ; Seo T. ; Honda Y. ; Tanaka S. ; Lee S. K. ; Ohto T. ; Yamada R J. Phys. Chem. Lett. 2019, 10, 3197. doi: 10.1021/acs.jpclett.9b00747
69	Yasini P. ; Afsari S. ; Peng H. ; Pikma P. ; Perdew J. P. ; Borguet E J. Am. Chem. Soc. 2019, 141, 10109. doi: 10.1021/jacs.9b05448
70	Stuyver T. ; Fias S. ; Geerlings P. ; De Proft F. ; Alonso M J. Phys. Chem. C 2018, 122, 19842. doi: 10.1021/acs.jpcc.8b01424
71	Ramos-Berdullas N. ; Graña A. M. ; Mandado M Theor. Chem. Acc. 2015, 134 doi: 10.1007/s00214-015-1620-z
72	Ramos-Berdullas N. ; Mandado M Chemistry 2013, 19, 3646. doi: 10.1002/chem.201203324
73	Chen W. ; Li H. ; Widawsky J. R. ; Appayee C. ; Venkataraman L. ; Breslow R J. Am. Chem. Soc. 2014, 136, 918. doi: 10.1021/ja411143s
74	Mahendran A. ; Gopinath P. ; Breslow R Tetrahedron Lett. 2015, 56, 4833. doi: 10.1016/j.tetlet.2015.06.076
75	Stuyver T. ; Perrin M. L. ; Geerlings P. ; Proft F. D. ; Alonso M J. Am. Chem. Soc. 2018, 140, 1313. doi: 10.1021/jacs.7b09464
76	Gil-Guerrero S. ; Ramos-Berdullas N. ; Mandado M Org. Electron. 2018, 61, 177. doi: 10.1016/j.orgel.2018.05.043
77	Zhang G. P. ; Xie Z. ; Song Y. ; Wei M. Z. ; Hu G. C. ; Wang C. K Org. Electron. 2017, 48, 29. doi: 10.1016/j.orgel.2017.05.032
78	Liu J. ; Zhao X. ; Al-Galiby Q. ; Huang X. ; Zheng J. ; Li R. ; Huang C. ; Yang Y. ; Shi J. ; Manrique D. Z Angew. Chem. Int. Ed. 2017, 56, 13061. doi: 10.1002/anie.201707710
79	Hua Y. ; Zhang H. ; Xia H Chin. J. Org. Chem. 2018, 38, 11.
	华煜晖; 张弘; 夏海平. 有机化学, 2018, 38, 11. doi: 10.6023/cjoc201709009
80	Pauly F. ; Viljas J. K. ; Cuevas J. C. ; Schön G Phys. Rev. B 2008, 77, 155312. doi: 10.1103/PhysRevB.77.155312
81	Huang B. ; Liu X. ; Yuan Y. ; Hong Z. W. ; Zheng J. F. ; Pei L. Q. ; Shao Y. ; Li J. F. ; Zhou X. S. ; Chen J J. Am. Chem. Soc. 2018, 140, 17685. doi: 10.1021/jacs.8b10450
82	Li Y. ; Buerkle M. ; Li G. ; Rostamian A. ; Wang H. ; Wang Z. ; Bowler D. R. ; Miyazaki T. ; Xiang L. ; Asai Y Nat. Mater. 2019, 18, 357. doi: 10.1038/s41563-018-0280-5
83	Quinn J. R. ; Foss F. W. ; Venkataraman L. ; Hybertsen M. S. ; Breslow R J. Am. Chem. Soc. 2007, 129, 6714. doi: 10.1021/ja0715804
84	Venkataraman L. ; Klare J. E. ; Nuckolls C. ; Hybertsen M. S. ; Steigerwald M. L Nature 2006, 442, 904. doi: 10.1038/nature05037
85	Huang J. R. ; Huang H. ; Tao C. P. ; Zheng J. F. ; Yuan Y. ; Hong Z. W. ; Shao Y. ; Niu Z. J. ; Chen J. Z. ; Zhou X. S Nanoscale Res. Lett. 2019, 14, 253. doi: 10.1186/s11671-019-3087-7
86	Chen Z. ; Chen L. ; Liu J. ; Li R. ; Tang C. ; Hua Y. ; Chen L. ; Shi J. ; Yang Y. ; Liu J J. Phys. Chem. Lett. 2019, 10, 3453. doi: 10.1021/acs.jpclett.9b00796
87	Mao J. C. ; Peng L. L. ; Li W. Q. ; Chen F. ; Wang H. G. ; Shao Y. ; Zhou X. S. ; Zhao X. Q. ; Xie H. J. ; Niu Z. J J. Phys. Chem. C 2017, 121, 1472. doi: 10.1021/acs.jpcc.6b10925
88	Zhen S. ; Mao J. C. ; Chen L. ; Ding S. ; Luo W. ; Zhou X. S. ; Qin A. ; Zhao Z. ; Tang B. Z Nano Lett. 2018, 18, 4200. doi: 10.1021/acs.nanolett.8b01082
89	Yang G. ; Wu H. ; Wei J. ; Zheng J. ; Chen Z. ; Liu J. ; Shi J. ; Yang Y. ; Hong W Chin. Chem. Lett. 2018, 29, 147. doi: 10.1016/j.cclet.2017.06.015
90	Li H. ; Garner M. H. ; Shangguan Z. ; Zheng Q. ; Su T. A. ; Neupane M. ; Li P. ; Velian A. ; Steigerwald M. L. ; Xiao S Chem. Sci. 2016, 7, 5657. doi: 10.1039/c6sc01360k
91	Garner M. H. ; Li H. ; Chen Y. ; Su T. A. ; Shangguan Z. ; Paley D. W. ; Liu T. ; Ng F. ; Li H. ; Xiao S Nature 2018, 558, 415. doi: 10.1038/s41586-018-0197-9
92	Widawsky J. R. ; Kamenetska M. ; Klare J. ; Nuckolls C. ; Steigerwald M. L. ; Hybertsen M. S. ; Venkataraman L Nanotechnology 2009, 20, 434009. doi: 10.1088/0957-4484/20/43/434009
93	Guo S. ; Hihath J. ; Diez-Perez I. ; Tao N J. Am. Chem. Soc. 2011, 133, 19189. doi: 10.1021/ja2076857
94	Isshiki Y. ; Fujii S. ; Nishino T. ; Kiguchi M J. Am. Chem. Soc. 2018, 140, 3760. doi: 10.1021/jacs.7b13694
95	Aragones A. C. ; Haworth N. L. ; Darwish N. ; Ciampi S. ; Bloomfield N. J. ; Wallace G. G. ; Diez-Perez I. ; Coote M. L Nature 2016, 531, 88. doi: 10.1038/nature16989
96	Zhang L. ; Laborda E. ; Darwish N. ; Noble B. B. ; Tyrell J. H. ; Pluczyk S. ; Le Brun A. P. ; Wallace G. G. ; Gonzalez J. ; Coote M. L J. Am. Chem. Soc. 2018, 140, 766. doi: 10.1021/jacs.7b11628
97	Li X. ; Hihath J. ; Chen F. ; Masuda T. ; Zang L. ; Tao N J. Am. Chem. Soc. 2007, 129, 11535. doi: 10.1021/ja072990v
98	Darwish N. ; Diez-Perez I. ; Da Silva P. ; Tao N. ; Gooding J. J. ; Paddon-Row M. N Angew. Chem. Int. Ed. 2012, 51, 3203. doi: 10.1002/anie.201107765
99	Osorio E. A. ; Bjornholm T. ; Lehn J. M. ; Ruben M. ; van der Zant H. S J. Phys. Condens. Matter 2008, 20, 374121. doi: 10.1088/0953-8984/20/37/374121
100	Brooke R. J. ; Szumski D. S. ; Vezzoli A. ; Higgins S. J. ; Nichols R. J. ; Schwarzacher W Nano Lett. 2018, 18, 1317. doi: 10.1021/acs.nanolett.7b04995
101	Yang Y. ; Liu J. ; Yan R. ; Wu D. ; Tian Z Chem. J. Chin. Univ. 2015, 36, 9.
	杨扬; 刘俊扬; 晏润文; 吴德印; 田中群. 高等学校化学学报, 2015, 36, 9. doi: 10.7503/cjcu20140941
102	Lee T. ; Wang W. ; Reed M. A Ann. New York Acad. Sci. 2003, 1006, 21. doi: 10.1196/annals.1292.001
103	Esposito T. ; Dinolfo P. H. ; Lewis K. M Org. Electron. 2018, 63, 58. doi: 10.1016/j.orgel.2018.08.040
104	Selzer Y. ; Cabassi M. A. ; Mayer T. S. ; Allara D. L Nanotechnology 2004, 15, S483. doi: 10.1088/0957-4484/15/7/057
105	Selzer Y. ; Cabassi M. A. ; Mayer T. S. ; Allara D. L J. Am. Chem. Soc. 2004, 126, 4052. doi: 10.1021/ja039015y
106	Taniguchi M. ; Morimoto K. ; Tsutsui M. ; Kawai T Chem. Lett. 2008, 37, 990. doi: 10.1246/cl.2008.990
107	Leary E. ; Höbenreich H. ; Higgins S. J. ; van Zalinge H. ; Haiss W. ; Nichols R. J. ; Finch C. M. ; Grace I. ; Lambert C. J. ; McGrath R Phys. Rev. Lett. 2009, 102, 086801. doi: 10.1103/PhysRevLett.102.086801
108	Fatemi V. ; Kamenetska M. ; Neaton J. B. ; Venkataraman L Nano Lett. 2011, 11, 1988. doi: 10.1021/nl200324e
109	Milan D. C. ; Al-Owaedi O. A. ; Oerthel M. C. ; Marqués-González S. ; Brooke R. J. ; Bryce M. R. ; Cea P. ; Ferrer J. ; Higgins S. J. ; Lambert C. J J. Phys. Chem. C 2015, 120, 15666. doi: 10.1021/acs.jpcc.5b08877
110	Gunasekaran S. ; Hernangomez-Perez D. ; Davydenko I. ; Marder S. ; Evers F. ; Venkataraman L Nano Lett. 2018, 18, 6387. doi: 10.1021/acs.nanolett.8b02743
111	Liu X. ; Sangtarash S. ; Reber D. ; Zhang D. ; Sadeghi H. ; Shi J. ; Xiao Z. Y. ; Hong W. ; Lambert C. J. ; Liu S. X Angew. Chem. Int. Ed. 2017, 56, 173. doi: 10.1002/anie.201609051
112	Xiao X. ; Xu B. ; Tao N J. Am. Chem. Soc. 2004, 126, 5370. doi: 10.1021/ja049469a
113	Scullion L. ; Doneux T. ; Bouffier L. ; Fernig D. G. ; Higgins S. J. ; Bethell D. ; Nichols R. J J. Phys. Chem. C 2011, 115, 8361. doi: 10.1021/jp201222b
114	Yang G. ; Sangtarash S. ; Liu Z. ; Li X. ; Sadeghi H. ; Tan Z. ; Li R. ; Zheng J. ; Dong X. ; Liu J Chem. Sci. 2017, 8, 7505. doi: 10.1039/c7sc01014a
115	Roldan D. ; Kaliginedi V. ; Cobo S. ; Kolivoska V. ; Bucher C. ; Hong W. ; Royal G. ; Wandlowski T J. Am. Chem. Soc. 2013, 135, 5974. doi: 10.1021/ja401484j
116	van der Molen S. J. ; Liao J. ; Kudernac T. ; Agustsson J. S. ; Bernard L. ; Calame M. ; van Wees B. J. ; Feringa B. L. ; Schönenberger C Nano Lett. 2009, 9, 76. doi: 10.1021/nl802487j
117	Huang C. ; Jevric M. ; Borges A. ; Olsen S. T. ; Hamill J. M. ; Zheng J. T. ; Yang Y. ; Rudnev A. ; Baghernejad M. ; Broekmann P. ;et al T., Yang Y., Rudnev A., Baghernejad M., Broekmann P., et al. Nat. Commun. 2017, 8, 15436. doi: 10.1038/ncomms15436
118	Leary E. ; Limburg B. ; Alanazy A. ; Sangtarash S. ; Grace I. ; Swada K. ; Esdaile L. J. ; Noori M. ; Gonzalez M. T. ; Rubio-Bollinger G J. Am. Chem. Soc. 2018, 140, 12877. doi: 10.1021/jacs.8b06338
119	Li J. J. ; Bai M. L. ; Chen Z. B. ; Zhou X. S. ; Shi Z. ; Zhang M. ; Ding S. Y. ; Hou S. M. ; Schwarzacher W. ; Nichols R. J. ;et al J. Am. Chem. Soc. 2015, 137, 5923. doi: 10.1021/ja512483y
120	Aragones A. C. ; Aravena D. ; Cerda J. I. ; Acis-Castillo Z. ; Li H. ; Real J. A. ; Sanz F. ; Hihath J. ; Ruiz E. ; Diez-Perez I Nano Lett. 2016, 16, 218. doi: 10.1021/acs.nanolett.5b03571
121	Iwane M. ; Fujii S. ; Nishino T. ; Kiguchi M J. Phys. Chem. C 2016, 120, 8936. doi: 10.1021/acs.jpcc.5b12728
122	Kiguchi M. ; Ohto T. ; Fujii S. ; Sugiyasu K. ; Nakajima S. ; Takeuchi M. ; Nakamura H J. Am. Chem. Soc. 2014, 136, 7327. doi: 10.1021/ja413104g
123	Leary E. ; Roche C. ; Jiang H. W. ; Grace I. ; Gonzalez M. T. ; Rubio-Bollinger G. ; Romero-Muniz C. ; Xiong Y. ; Al-Galiby Q. ; Noori M J. Am. Chem. Soc. 2018, 140, 710. doi: 10.1021/jacs.7b10542
124	Nichols R. J. ; Higgins S. J Acc. Chem. Res. 2016, 49, 2640. doi: 10.1021/acs.accounts.6b00373
125	Liu J. ; Huang X. ; Wang F. ; Hong W Acc. Chem. Res. 2019, 52, 151. doi: 10.1021/acs.accounts.8b00429
126	Chen L. ; Feng A. ; Wang M. ; Liu J. ; Hong W. ; Guo X. ; Xiang D Sci. China Chem. 2018, 61, 1368. doi: 10.1007/s11426-018-9356-2
127	Gu C. ; Guo X Acta Phys. -Chim. Sin. 2017, 33, 1927.
	顾春晖; 郭雪峰. 物理化学学报, 2017, 33, 1927. doi: 10.3866/PKU.WHXB201706144
128	Šebera J. ; Lindner M. ; Gasior J. ; Mészáros G. ; Fuhr O. ; Mayor M. ; Valášek M. ; Kolivoška V. ; Hromadová M Nanoscale 2019, 11, 12959. doi: 10.1039/c9nr04071d
129	Zhang W. ; Gan S. ; Vezzoli A. ; Davidson R. J. ; Milan D. C. ; Luzyanin K. V. ; Higgins S. J. ; Nichols R. J. ; Beeby A. ; Low P. J ACS Nano 2016, 10, 5212. doi: 10.1021/acsnano.6b00786
130	Chang S. ; He J. ; Lin L. ; Zhang P. ; Liang F. ; Young M. ; Huang S. ; Lindsay S Nanotechnology 2009, 20, 185102. doi: 10.1088/0957-4484/20/18/185102
131	Chang S. ; Huang S. ; He J. ; Liang F. ; Zhang P. ; Li S. ; Chen X. ; Sankey O. ; Lindsay S Nano Lett. 2010, 10, 1070. doi: 10.1021/nl1001185
132	Chang S. ; He J. ; Kibel A. ; Lee M. ; Sankey O. ; Zhang P. ; Lindsay S Nat. Nanotechnol. 2009, 4, 297. doi: 10.1038/nnano.2009.48
133	Huang S. ; He J. ; Chang S. ; Zhang P. ; Liang F. ; Li S. ; Tuchband M. ; Fuhrmann A. ; Ros R. ; Lindsay S Nat. Nanotechnol. 2010, 5, 868. doi: 10.1038/nnano.2010.213
134	Wheeler D. A. ; Srinivasan M. ; Egholm M. ; Shen Y. ; Chen L. ; McGuire A. ; He W. ; Chen Y. J. ; Makhijani V. ; Roth G. T Nature 2008, 452, 872. doi: 10.1038/nature06884

Techniques	Categories	Nanogap between the electrodes	Single molecule level?	Advantages	Disadvantages
Fixed junction	Electromigration	~1 nm ⁶	Possible (when the length of molecule is approximately equal to the size of nanogap)	High reproducibility ⁶, High stability, Belonging to nano-scale devices, Nanogap can be characterized with precision	Difficulty in repeatedly obtaining single molecule junctions, Needing nano fabrication, Low compatibility with different lengths of investigated molecules
	On-wire lithography	2 to several hundred nanometers ^{3, 4}	Possible (when the length of molecule is approximately equal to the size of nanogap)	High stability, Belonging to nano-scale devices, Nanogap can be characterized with precision	Difficulty in accurately controlling the gap distance, Difficulty in repeatedly obtaining single molecule junctions, Needing nano fabrication, Low compatibility with different lengths of investigated molecules
	STM-FJ	0–3 nm	Yes	The size of nanogap can be conveniently adjusted，High stability	For unknown molecules, a range of gap size needs to be characterized to determine the optimal gap conditions for single molecule conductance measurements
Break junction	STM-BJ	In the process of dynamic change	Yes	Fast creation of repeated molecular junctions	Needing repeatedly breaking metal contacts, thus limiting the metal selection, Difficulty in constructing molecular junctions with different metal electrode materials ⁵⁸
Break junction	MCBJ	In the process of dynamic change	Yes	Fast creation of repeated molecular junctions	Needing repeatedly breaking metal contacts, thus limiting the metal selection, Difficulty in constructing molecular junctions with different metal electrode materials ⁵⁸

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Techniques and Influencing Factors for Single Molecule Electronic Conductance Measurements

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