物理化学学报 >> 2010, Vol. 26 >> Issue (07): 1837-1841.doi: 10.3866/PKU.WHXB20100703

结构化学 上一篇    下一篇

β-环糊精与系列无机盐分子-离子加合物的粉末X射线衍射分析

党政, 宋乐新   

  1. 中国科学技术大学高分子科学与工程学系, 中国科学院软物质化学重点实验室, 合肥 230026
  • 收稿日期:2009-10-26 修回日期:2010-01-14 发布日期:2010-07-02
  • 通讯作者: 宋乐新 E-mail:solexin@ustc.edu.cn

Powder X-Ray Diffraction Analyses for Molecule-Ion Adducts of β-Cyclodextrin with a Series of Inorganic Salts

DANG Zheng, SONG Le-Xin   

  1. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, P. R. China
  • Received:2009-10-26 Revised:2010-01-14 Published:2010-07-02
  • Contact: SONG Le-Xin E-mail:solexin@ustc.edu.cn

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摘要：

糖类物质和无机盐之间的分子-离子相互作用无论是在生物物理学还是在生物化学方面都有很重要的意义. 本文利用粉末X射线衍射法(PXRD)来考察β-环糊精(β-CD)与一系列无机盐加合物之间的分子-离子相互作用. 结果显示, 同系无机盐与β-CD加合物的PXRD谱之间存在着微妙的差异性. 这些PXRD谱主要反映β-CD的堆积方式, 因此, 它们的差异性揭示了分子-离子相互作用的多样性与复杂性. 造成PXRD谱差异性的影响因素包括制备条件、阴离子和阳离子的性质、离子电荷等. 由糖和盐之间的分子-离子相互作用所诱导的结晶行为多样性将为碳水化合物在生物物理、分子生物学、临床医学、纳米科学与技术等方面的学术与应用研究提供重要的启示.

关键词: β-环糊精, 加合物, 分子-离子相互作用, 无机盐, 粉末X射线衍射

Abstract:

The molecule-ion interaction between a sugar and a salt is important and significant in biophysics and biochemistry. In this paper, powder X-ray diffraction (PXRD) technology was used to examine the molecule-ion adducts of a series of inorganic salts with β-cyclodextrin (β-CD). Our results indicate that there are considerable differences in the spectral properties of the PXRDs for adducts formed by similar inorganic salts and β-CD. Since their PXRD patterns are mainly dominated by β-CD, the large difference in spectral behavior reflects the diversity and complexity of molecule-ion interactions. The spectral differences were carefully compared by considering several factors such as the formation conditions of crystal adducts, the nature of the anions or cations and ionic charges. The diversity and complexity in adduct behaviors between sugars and salts in the crystal state should be very useful for scientific research and for the practical application of carbohydrates in biophysical chemistry, molecular biology, clinical medicine, nanoscience, and technology.

Key words: β-Cyclodextrin, Adduct, Molecule-ion interaction, Inorganic salt, Powder X-ray diffraction