物理化学学报 >> 1994, Vol. 10 >> Issue (09): 831-837.doi: 10.3866/PKU.WHXB19940912

研究论文 上一篇    下一篇

辅酶B12模型化合物生成与解离电化学研究(II)

郑国栋, 阎雁, 王英, 黄楚宝, 高德, 安庆大   

  1. 吉林大学化学系，长春 130023|湖南大学化工系，长沙 410082|大连轻工业学院，大连 116034
  • 收稿日期:1993-08-16 修回日期:1994-05-03 发布日期:1994-09-15
  • 通讯作者: 郑国栋

Studies on the Production and Dissociation of Coenzyme B12 Models by Electrochemistry and Spectroelectrochemistry(II)

Zheng Guo-Dong, Yan Yan, Wang Ying, Huang Chu-Bao, Gao De, An Qing-Da   

  1. Department of Chemistry,Jilin University,Changchun 130023|Department of Chemical Engineering,Hunan University,Changsha 410082|Dalian Institute of Light Industry,Dalian 116034
  • Received:1993-08-16 Revised:1994-05-03 Published:1994-09-15
  • Contact: Zheng Guo-Dong

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摘要：

用电化学方法研究了钴卟啉与多种直键溴代烷的相互作用，表明Ⅰ价钴卟啉可以与溴代烷形成有σ钴-碳键的输酶B12模型化合物．计算了Ⅰ价钴卟啉与各种直键溴代烷的加合速率常数．详细讨论了直键烷烃的链长与模型化合物生成速率及烷基钴卟啉负离子稳定性的关系．讨论了几种模型化合物的优劣．

关键词: 辅酶B12模型化合物, 钴卟啉, 电化学

Abstract:

The reaction of CoTPP (cobalt tetrophenylporphyrin) with various alkyl bromides [CH3CH2Br; CH3(CH2)3Br; CH3(CH2)7Br; CH3(CH2)11Br; CH3(CH2)15Br] were studied by cyclic voltammogram. The reaction of [Co(I )TPP]- with alkyl bromide formed coenzym B12 moddel compound containing a cobalt-carbon bond. The formation rate constants are 2.43; 16.73; 28.30; 35.05; 42.36 mol-1•L•s-1 respectively. The relation between the chain length of alkyl bromide the rate constants and the stability of alkyl cobalt porphyrin negtive ion were discussed.

Key words: Coenzyme B12 model compound, Electrochemistry, Cobalt prphyrin