物理化学学报 >> 2007, Vol. 23 >> Issue (05): 713-716.doi: 10.3866/PKU.WHXB20070517

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LB膜中的缺陷畴区及其诱导形成环形草酸钙图形

邓穗平; 欧阳健明   

  1. 暨南大学生物矿化与结石病防治研究所, 广州 510632
  • 收稿日期:2006-11-06 修回日期:2006-12-21 发布日期:2007-04-28
  • 通讯作者: 欧阳健明 E-mail:toyjm@jnu.edu.cn

Defective Domains in LB Filmand Its Induction Growth of Ring-shaped CalciumOxalate Patterns

DENG Sui-Ping; OUYANG Jian-Ming   

  1. nstitute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632, P. R. China
  • Received:2006-11-06 Revised:2006-12-21 Published:2007-04-28
  • Contact: OUYANG Jian-Ming E-mail:toyjm@jnu.edu.cn

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摘要： 利用存在缺陷的LB膜来模拟受损伤的肾上皮细胞膜诱导肾结石矿物草酸钙(CaOxa)晶体生长. 经2.5 mmol·L-1的草酸钾溶液对二棕榈酰磷脂酰胆碱(DPPC)的LB膜进行处理后, 可强化LB膜中液态扩张相(LE)和液态凝聚相(LC)之间的结构差异, 原子力显微镜(AFM)证实了圈状缺陷的存在. 以LB膜的圈状缺陷为模板, 诱导了一水草酸钙(COM)晶体环状图案. 相比之下, 未经草酸钾处理的LB膜只诱导生成零散的六边形COM晶体.

关键词: 缺陷LB膜, 生物矿化, 草酸钙, AFM

Abstract: Defective LB film was used as model for injured renal epithelial membrane to induce the growth of calcium oxalate monohydrate (COM) crystals, which was the major inorganic component found in renal calculi. After the LB film of dipalmitoylphosphatidylcholine (DPPC) was treated by 2.5 mmol·L-1 potassium oxalate, the structural differentiation between liquid expanded (LE) phase and liquid condensed (LC) phase in LB film was strengthened and circular defects appeared. These circular defects were proved by atomic force microscopy (AFM). Such circular defects could induce ring-shaped patterns of COM crystals. In comparison, the LB films without pretreatment by potassium oxalate only induced randomly growth of COMcrystals.

Key words: Defective LB Film, Biomineralization, Calciumoxalate, AFM