二维材料“遇见”生物大分子：机遇与挑战

doi:10.3866/PKU.WHXB201812057

物理化学学报 >> 2019, Vol. 35 >> Issue (10): 1078-1089.doi: 10.3866/PKU.WHXB201812057

所属专题：二维材料及器件

二维材料“遇见”生物大分子：机遇与挑战

杜春保^1,*(),胡小玲²,张刚³,程渊^3,*()

¹ 西安石油大学化学化工学院，西安 710065
² 西北工业大学理学院，西安 710072
³ 新加坡科技研究局高性能计算研究所，新加坡 138632

收稿日期:2018-12-31 录用日期:2019-01-24 发布日期:2019-01-29
通讯作者: 杜春保,程渊 E-mail:duchunbao218@126.com;chengy@ihpc.a-star.edu.sg
作者简介:杜春保，1988年生。2017年在西北工业大学获得博士学位。现就职于西安石油大学。主要研究方向为纳米材料生物效应、功能高分子材料与多孔材料催化。|程渊，1981生。2003年在复旦大学获得学士学位；2008年在新加坡国立大学获得博士学位。现任新加坡科技研究局高性能计算研究所科学家。主要研究方向为纳米材料跨尺度模拟、仿生材料力学行为与应用。
基金资助:
国家自然科学基金(51433008);高级制造与工程(A1898b0043)

2D Materials Meet Biomacromolecules: Opportunities and Challenges

Chunbao DU^1,*(),Xiaoling HU²,Gang ZHANG³,Yuan CHENG^3,*()

¹ College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, P. R. China
² School of Natural and Applied Sciences, Northwestern Polytechnical University, Xi'an 710072, P. R. China
³ Institute of High Performance Computing, A*STAR, 138632, Singapore

Received:2018-12-31 Accepted:2019-01-24 Published:2019-01-29
Contact: Chunbao DU,Yuan CHENG E-mail:duchunbao218@126.com;chengy@ihpc.a-star.edu.sg
Supported by:
The project was supported by the National Natural Science Foundation of China(51433008);the RIE2020 Advanced Manufacturing and Engineering (AME) Programmatic grant, Work Package 4(A1898b0043)

摘要/Abstract

摘要：

二维材料的超薄原子层结构使其具有独特的力学性能、导热导电性以及巨大的比表面积，在能源存储、催化、传感和生物医学等领域引起了国内外学者的广泛关注。将二维材料与具有生物活性的生物大分子相结合可以为开发具有优异电学、力学和生物学功能的特种功能材料提供新的方法和途径。近年来，科研工作者针对这一方向展开了广泛的研究，取得了一系列重要的成果，使二维材料与生物大分子的结合与应用成为了新的研究热点。本文综述了近年来二维材料和生物大分子之间的相互作用及应用的研究进展，重点介绍了二维材料与生物大分子在分子水平上的相互作用机理，还总结了基于二维材料与生物大分子之间的相互作用在工程、疾病治疗和抗菌中的应用，并对其未来的研究趋势提出了展望。

关键词: 二维材料, 生物大分子, 非共价键, 共价键, 应用

Abstract:

With the rapid development of science and technology, various nanomaterials have continually emerged to meet human needs. As a newly emerging class of nanomaterials, two-dimensional (2D) materials have received wide attention recently in energy storage, catalysis, sensing and biomedicine due to their unique features such as good mechanical property, high specific surface area, excellent thermal and electrical conductivity. Biomacromolecules are the special organic molecules with various biological activities which exist extensively in every aspect of human life. When 2D materials meet biomacromolecules to display their own unique advantages, more opportunities and challenges have arisen for the exploitation and fabrication of novel nanomaterials with unique electrical, mechanical, biological properties and specific functions. In recent years, extensive research has been carried out with outstanding achievement thus the combination of 2D materials and biomacromolecules becomes a new hotspot. There were generally two binding interactions between 2D materials and biomacromolecules, namely non-covalent binding (electrostatic interaction, hydrophobic effect, π–π stacking, van der Waals interaction) and covalent binding (special chemical reactions between the functional groups of 2D materials and biomacromolecules). In addition, due to the excellent photothermal conversion performance, 2D materials could exhibit a non-contact interaction to biomacromolecules through the photo-thermal effect which has greatly broadened their applications. Up to now, numerous studies have clearly revealed the binding and effect mechanism and the research will be more focused on expanding the scope and application. Currently, the combination of 2D materials and biomacromolecules has widely involved in many cutting-edge applications such as flexible device, biosensor, smart skin, drug delivery, antibacterial, disease therapy and so on. Although a lot of progress has been made, several highlight open questions still need to be urgently addressed, such as the production cost of 2D materials, biological activity of biomacromolecules, stability and biocompatibility of 2D/biomacromolecule nanomaterials. This review summarizes the interactions between some typical 2D materials (i.e. graphene, graphene oxide, nitrogen-doped graphene, molybdenum disulfide, phosphorene, silylene and germanene) and biomacromolecules (i.e. silk protein, lysozyme, bovine serum albumin, bovine hemoglobin, ovalbumin, villin, bovine fibrinogen, DNA/RNA, glucose oxidase and chitosan) and focuses on the recent progress of some typical applications (i.e. engineering application, disease therapy and antibacterial). The non-covalent and covalent bindings of 2D materials and biomacromolecules are discussed in detail, and the applications of the combination of 2D materials and biomacromolecules in engineering and bioscience have been reviewed. Finally, the challenges for the future development of 2D materials and biomacromolecules are also briefly proposed.

10.3866/PKU.WHXB201809013.F009

Key words: Two-dimensional material, Biomacromolecule, Non-covalence, Covalence, Application

杜春保,胡小玲,张刚,程渊. 二维材料“遇见”生物大分子：机遇与挑战[J]. 物理化学学报, 2019, 35(10), 1078-1089. doi: 10.3866/PKU.WHXB201812057

Chunbao DU,Xiaoling HU,Gang ZHANG,Yuan CHENG. 2D Materials Meet Biomacromolecules: Opportunities and Challenges[J]. Acta Physico-Chimica Sinica 2019, 35(10), 1078-1089. doi: 10.3866/PKU.WHXB201812057

链接本文: https://www.whxb.pku.edu.cn/CN/10.3866/PKU.WHXB201812057

https://www.whxb.pku.edu.cn/CN/Y2019/V35/I10/1078

图/表 5

图1

图2

图3

图4

表1

参考文献 116

1	Zhang Z. ; Chen P. ; Duan X. ; Zang K. ; Luo J. ; Duan X. Science 2017, 357, 788. doi: 10.1126/science.aan6814
2	Lang H. ; Zhang S. ; Liu Z. Phys. Rev. B 2016, 94, 235306. doi: 10.1103/PhysRevB.94.235306
3	Zhang G. ; Zhang Y. W. Chin. Phys. B 2017, 26, 034401. doi: 10.1088/1674-1056/26/3/034401
4	Zhang G. ; Zhang Y. W. J. Mater. Chem. C 2017, 5, 7684. doi: 10.1039/c7tc01088e
5	Zhang G. ; Zhang Y. W. Mech. Mater. 2015, 91, 382. doi: 10.1016/j.mechmat.2015.03.009
6	Xie G. ; Ju Z. ; Zhou K. ; Wei X. ; Guo Z. ; Cai Y. ; Zhang G. NPJ Comput. Mater. 2018, 4, 21. doi: 10.1038/s41524-018-0076-9
7	Liu Q. ; Wang X. ; Wang J. ; Huang X. Acta Phys.-Chim. Sin. 2019, 35, 1099. doi: 10.3866/PKU.WHXB201811005
	刘强; 王晓珊; 王加亮; 黄晓. 物理化学学报, 2019, 35, 1099. doi: 10.3866/PKU.WHXB201811005
8	Ouyang F. ; Peng S. ; Yang Z. ; Chen Y. ; Zou H. ; Xiong X. Phys. Chem. Chem. Phys. 2014, 16, 20524. doi: 10.1039/C4CP02090A
9	Zhang S. ; Wang J. ; Li Z. ; Zhao R. ; Tong L. ; Liu Z. ; Zhang J. ; Liu Z. J. Phys. Chem. C 2016, 120, 10605. doi: 10.1021/acs.jpcc.5b12388
10	Zhou L. ; Liao L. ; Wang J. ; Yu J. ; Li D. ; Xie Q. ; Liu Z. ; Yang Y. ; Guo X. ; Liu Z. Adv. Mater. 2016, 28, 2148. doi: 10.1002/adma.201670070
11	Li Z. ; Liu Z. ; Liu Z. Nano Res. 2017, 10, 2005. doi: 10.1007/s12274-016-1388-z
12	Liu N. ; Zhou S. ; Zhao J. Acta Phys.-Chim. Sin. 2019, 35, 1142. doi: 10.3866/PKU.WHXB201810040
	刘南舒; 周思; 赵纪军. 物理化学学报, 2019, 35, 1142. doi: 10.3866/PKU.WHXB201810040
13	Wang K. ; Shi L. ; Wang M. ; Yang H. ; Liu Z. ; Peng H. Acta Phys.-Chim. Sin. 2019, 35, 1112. doi: 10.3866/PKU.WHXB201805032
	王可心; 史刘嵘; 王铭展; 杨皓; 刘忠范; 彭海琳. 物理化学学报, 2019, 35, 1112. doi: 10.3866/PKU.WHXB201805032
14	Qin G. ; Du A. ; Sun Q. Energy Technol.-Ger 2018, 6, 205. doi: 10.1002/ente.201700413
15	Zhao R. ; Li F. ; Liu Z. ; Liu Z. ; Ding F. Phys. Chem. Chem. Phys. 2015, 17, 29327. doi: 10.1039/c5cp04833h
16	Zhao R. ; Zhao X. ; Liu Z. ; Ding F. ; Liu Z. Nanoscale 2017, 9, 3561. doi: 10.1039/c6nr09368j
17	Wei X. ; Wang Y. ; Shen Y. ; Xie G. ; Xiao H. ; Zhong J. ; Zhang G. Appl. Phys. Lett. 2014, 105, 103902. doi: 10.1063/1.4895344
18	Li W. ; Zhang G. ; Guo M. ; Zhang Y. W. Nano Res. 2014, 7, 518. doi: 10.1007/s12274-014-0418-y
19	Ouyang F. ; Yang Z. ; Ni X. ; Wu N. ; Chen Y. ; Xiong X. Appl. Phys. Lett. 2014, 104, 071901. doi: 10.1063/1.4865902
20	Li W. ; Guo M. ; Zhang G. ; Zhang Y. W. Phys. Rev. B 2014, 89, 205402. doi: 10.1103/PhysRevB.89.205402
21	Li W. ; Yang Y. ; Weber J. ; Zhang G. ; Zhou R. ACS Nano 2016, 10, 1829. doi: 10.1021/acsnano.5b05250
22	Zhu P. ; Chen Y. ; Zhou Y. ; Yang Z. ; Wu D. ; Xiong X. ; Ouyang F. Int. J. Hydrogen. 2018, 43, 14087. doi: 10.1016/j.ijhydene.2018.05.175
23	Liu X. ; Wang J. ; Xu C. ; Luo J. ; Liang D. ; Cen Y. ; Lü Y. ; Li Z. Acta Phys.-Chim. Sin. 2019, 35, 1134. doi: 10.3866/PKU.WHXB201809013
	刘新科; 王佳乐; 许楚瑜; 罗江流; 梁迪斯; 岑俞诺; 吕有明; 李治文. 物理化学学报, 2019, 35, 1134. doi: 10.3866/PKU.WHXB201809013
24	Zhu Z. ; Cheng Y. ; Schwingenschögl U. Phys. Rev. Lett. 2013, 110, 077202. doi: 10.1103/PhysRevLett.110.077202
25	Jing Y. ; Zhou Z. ; Cabrera C. R. C. ; Chen Z. J. Phys. Chem. C 2013, 117, 25409. doi: 10.1021/jp410969u
26	Gan L. Y. ; Zhang L. H. ; Zhang Q. ; Guo C. S. ; Schwingenschögl U. ; Zhao Y. Phys. Chem. Chem. Phys. 2016, 18, 3080. doi: 10.1039/c5cp05695k
27	Zhang M. ; Zhu Y. ; Wang X. ; Feng Q. ; Qiao S. ; Wen W. ; Chen Y. ; Cui M. ; Zhang J. ; Cai C. ; et al J. Am. Chem. Soc. 2015, 137, 7051. doi: 10.1021/jacs.5b03807
28	Rivera P. ; Schaibley J. R. ; Jones A. M. ; Ross J. S. ; Wu S. ; Aivazian G. ; Klement P. ; Seyler K. ; Clark G. ; Ghimire N. J. ; et al Nat. Commun. 2015, 6, 6242. doi: 10.1038/ncomms7242
29	Huang C. ; Wu S. ; Sanchez A. M. ; Peters J. J. P. ; Beanland R. ; Ross J. S. ; Rivera P. ; Yao W. ; Cobden D. H. ; Xu X. Nat. Mater. 2013, 13, 1096. doi: 10.1038/nmat4064
30	Xi X. ; Zhao L. ; Wang Z. ; Berger H. ; Forró L. ; Shan J. ; Mak K. F. Nat. Nanotechnol. 2015, 10, 765. doi: 10.1038/nnano.2015.143
31	Checkelsky J. G. ; Hor Y. S. ; Cava R. J. ; Ong N. P. Phys. Rev. Lett. 2011, 106, 196801. doi: 10.1103/PhysRevLett.106.196801
32	Zhou L. ; Xu K. ; Zubair A. ; Liao A. D. ; Fang W. ; Ouyang F. ; Lee Y. H. ; Ueno K. ; Saito R. ; Palacios T. ; et al J. Am. Chem. Soc. 2015, 137, 11892. doi: 10.1021/jacs.5b07452
33	Zhou L. ; Zubair A. ; Wang Z. ; Zhang X. ; Ouyang F. ; Fang W. ; Ueno K. ; Li J. ; Palacios T. ; Kong J. ; Dresselhaus M. S. Adv. Mater. 2016, 28, 9526. doi: 10.1002/adma.201602687
34	Zhou L. ; Xu K. ; Zubair A. ; Zhang X. ; Ouyang F. ; Palacios T. ; Dresselhaus M. ; Li Y. ; Kong J. Adv. Funct. Mater. 2017, 27, 1603491. doi: 10.1002/adfm.201603491
35	Ha Y. E. ; Jo M. Y. ; Park J. ; Kang Y. C. ; Yoo S. I. ; Kim J. H. J. Phys. Chem. C 2013, 117, 2646. doi: 10.1021/jp311148d
36	Wu D. ; Zheng X. ; Chen X. ; Xie Q. ; Shi J. ; Huang Y. ; Zhang X. ; Ouyang F. ; Gao Y. ; Huang H. J. Phys. Chem. C 2018, 122, 1860. doi: 10.1021/acs.jpcc.7b10666
37	Zhou P. ; Xu Q. ; Li H. ; Wang Y. ; Yan B. ; Zhou Y. ; Chen J. ; Zhang J. ; Wang K. Angew. Chem. Int. Ed. Engl. 2015, 54, 15226. doi: 10.1002/anie.201508216
38	Li S. L. ; Yin H. ; Kan X. ; Gan L. Y. ; Schwingenschögl U. ; Zhao Y. Phys. Chem. Chem. Phys. 2017, 19, 30069. doi: 10.1039/c7cp05195f
39	Li W. ; Yang Y. ; Zhang G. ; Zhang Y. W. Nano Lett. 2015, 15, 1691. doi: 10.1021/nl504336h
40	Cai Y. ; Ke Q. ; Zhang G. ; Yakobson B. I. ; Zhang Y. W. J. Am. Chem. Soc. 2016, 138, 10199. doi: 10.1021/jacs.6b04926
41	Shi R. ; Dai X. ; Li W. ; Lu F. ; Liu Y. ; Qu H. ; Li H. ; Chen Q. ; Tian H. ; Wu E. ACS Nano 2017, 11, 9500. doi: 10.1021/acsnano.7b05328
42	Zhang S. ; Mao N. ; Wu J. ; Tong L. ; Zhang J. ; Liu Z. Small 2017, 13, 1700466. doi: 10.1002/smll.201700466
43	Cheng Y. ; Zhang G. ; Zhang Y. ; Chang T. ; Pei Q. X. ; Cai Y. ; Zhang Y. W. Nanoscale 2018, 10, 1660. doi: 10.1039/c7nr07226k
44	Hu M. ; Yang Z. ; Zhou W. ; Li A. ; Pan J. ; Ouyang F. Phys. E 2018, 98, 60. doi: 10.1016/j.physe.2017.12.027
45	Liu Z. Acta Phys.-Chim. Sin. 2016, 32, 1053. doi: 10.3866/PKU.WHXB201603302
	刘忠范. 物理化学学报, 2016, 32, 1053. doi: 10.3866/PKU.WHXB201603302
46	Yin H. ; Xiang G. ; Yue L. ; Zhang H. Acta Phys.-Chim. Sin. 2015, 31, 67. doi: 10.3866/PKU.WHXB201411211
	尹海峰; 向功周; 岳莉; 张红. 物理化学学报, 2015, 31, 67. doi: 10.3866/PKU.WHXB201411211
47	Li L. ; Lu S. Z. ; Pan J. ; Qin Z. ; Wang Y. Q. ; Wang Y. ; Cao G. Y. ; Du S. ; Gao H. J. Adv. Mater. 2014, 26, 4820. doi: 10.1002/adma.201400909
48	Chen J. ; Ge Y. ; Zhou W. ; Peng M. ; Pan J. ; Ouyang F. J. Phys.-Condens. Mat. 2018, 30, 245701. doi: 10.1088/1361-648x/aac186
49	Chen J. ; Yang Z. ; Zhou W. ; Zou H. ; Li M. ; Ouyang F. Phys. Status. Solidi.-R. 2018, 12, 1800038. doi: 10.1002/pssr.201800038
50	Wu H. ; Yan Z. Acta Phys.-Chim. Sin. 2019, 35, 1052. doi: 10.3866/PKU.WHXB201801262
	吴昊; 严仲. 物理化学学报, 2019, 35, 1052. doi: 10.3866/PKU.WHXB201801262
51	Xi J. ; Nakamura Y. ; Zhao T. ; Wang D. ; Shuai Z. Acta Phys.-Chim. Sin. 2018, 34, 961. doi: 10.3866/PKU.WHXB201802051
	奚晋扬; 中村悠马; 赵天琦; 王冬; 帅志刚. 物理化学学报, 2018, 34, 961. doi: 10.3866/PKU.WHXB201802051
52	Shi L. ; Yao D. ; Zhang G. ; Li B. Appl. Phys. Lett. 2010, 96, 173108. doi: 10.1063/1.3421543
53	Chen D. ; Pei Q. Chem. Rev. 2017, 117, 11239. doi: 10.1021/acs.chemrev.7b00019
54	Chhowalla M. ; Liu Z. ; Zhang H. Chem. Soc. Rev. 2015, 44, 2584. doi: 10.1039/c5cs90037a
55	Chen P. ; Zhang Z. ; Duan X. ; Duan X. Chem. Soc. Rev. 2018, 47, 3129. doi: 10.1039/C7CS00887B
56	Xie G. ; Ding D. ; Zhang G. Adv. Phys. X 2018, 3, 1480417. doi: 10.1080/23746149.2018.1480417
57	Du C. ; Hu X. ; Guan P. ; Guo L. ; Qian L. ; Li J. ; Song R. ; Tang Y. J. Mater. Sci. 2015, 50, 427. doi: 10.1007/s10853-014-8602-8
58	Du C. ; Hu X. ; Guan P. ; Guo L. ; Qian L. ; Song R. ; Li J. ; Wang C. J. Mater. Chem. B 2015, 3, 3044. doi: 10.1039/c4tb02030h
59	Du C. ; Hu X. ; Guan P. ; Gao X. ; Song R. ; Li J. ; Qian L. ; Zhang N. ; Guo L. J. Mater. Chem. B 2016, 4, 1510. doi: 10.1039/c5tb02633d
60	Du C. ; Zhang N. ; Ding S. ; Gao X. ; Guan P. ; Hu X. Polym. Chem. 2016, 7, 4531. doi: 10.1039/c6py00747c
61	Du C. ; Hu X. ; Cheng Y. ; Gao J. ; Zhang Y. W. ; Su K. ; Li Z. ; Zhang N. ; Chang N. ; Zeng K. Mat. Sci. Eng. C 2018, 169. doi: 10.1016/j.msec.2017.10.002
62	Zhang N. ; Hu X. ; Guan P. ; Du C. ; Li J. ; Qian L. ; Zhang X. ; Ding S. ; Li B. Chem. Eng. J. 2017, 317, 356. doi: 10.1016/j.cej.2017.02.066
63	Cheng Y. ; Koh L. D. ; Li D. ; Ji B. ; Zhang Y. ; Yeo J. ; Guan G. ; Han M. Y. ; Zhang Y. W. ACS Appl. Mater. Interfaces 2015, 7, 21787. doi: 10.1021/acsami.5b05615
64	Cheng Y. ; Koh L. D. ; Li D. ; Ji B. ; Han M. Y. ; Zhang Y. W. J. R. Soc. Interface 2014, 11, 20140305. doi: 10.1098/rsif.2014.0305
65	Xu C. ; Li D. ; Cheng Y. ; ·Liu M. ; Zhang Y. W. ; Ji B. Acta Mech. Sin. 2015, 31, 416. doi: 10.1007/s10409-015-0404-y
66	Wang F. ; Aravind S. S. J. ; Wu H. ; Forys J. ; Venkataraman V. ; Ramanujachary K. ; Hu X. Mat. Sci. Eng. C 2017, 79, 728. doi: 10.1016/j.msec.2017.05.120
67	Zhang N. ; Hu X. ; Guan P. ; Zeng K. ; Cheng Y. J. Phys. Chem. C 2019, 123, 897. doi: 10.1021/acs.jpcc.8b09893
68	Zuo G. ; Zhou X. ; Huang Q. ; Fang H. ; Zhou R. J. Phys. Chem. C 2011, 115, 23323. doi: 10.1021/jp208967t
69	Chong Y. ; Ge C. ; Yang Z. ; Garate J. A. ; Gu Z. ; Weber J. K. ; Liu J. ; Zhou R. ACS Nano 2015, 9, 5713. doi: 10.1021/nn5066606
70	Tu Y. ; Lv M. ; Xiu P. ; Huynh T. ; Huang Q. ; Fan C. ; Zhang M. ; Fang H. ; Zhou R. Nat. Nanotechnol. 2013, 8, 594. doi: 10.1038/NNANO.2013.125
71	Wang Q. ; Zhai X. ; Crowe M. ; Gou L. ; Li Y. ; Li D. ; Zhang L. ; Diao J. ; Ji B. Sci. China Phys. Mech. 2019, 62, 64611. doi: 10.1007/s11433-018-9317-7
72	Li B. ; Li W. ; Perez-Aguilar J. M. ; Zhou R. Small 2017, 13, 1603685. doi: 10.1002/smll.201603685
73	Gu Z. ; Zhao L. ; Liu S. ; Duan G. ; Perez-Aguilar J. M. ; Luo J. ; Li W. ; Zhou R. ACS Nano 2017, 11, 3198. doi: 10.1021/acsnano.7b00236
74	Gu Z. ; Li W. ; Hong L. ; Zhou R. J. Chem. Phys. 2016, 144, 175103. doi: 10.1063/1.4948459
75	Li W. ; Guo M. ; Zhang G. ; Zhang Y. W. Chem. Mater. 2014, 26, 5625. doi: 10.1021/cm5021756
76	Liu Y. ; Wu H. ; Cheng H. C. ; Yang S. ; Zhu E. ; He Q. ; Ding M. ; Li D. ; Guo J. ; Weiss N. ; et al Nano Lett. 2015, 15, 3030. doi: 10.1021/nl504957p
77	Liu X. ; Gao J. ; Zhang G. ; Zhang Y. W. Nano Res. 2017, 10, 2944. doi: 10.1007/s12274-017-1504-8
78	Yang Z. ; Pan J. ; Liu Q. ; Wu N. ; Hu M. ; Ouyang F. Phys. Chem. Chem. Phys. 2017, 19, 1303. doi: 10.1039/c6cp07327a
79	Wang X. ; Li B. ; Bell D. R. ; Li W. ; Zhou R. J. Mater. Chem. A 2017, 5, 23020. doi: 10.1039/C7TA05995G
80	Liang J. ; Zhang J. ; Li Z. ; Hong H. ; Wang J. ; Zhang Z. ; Zhou X. ; Qiao R. ; Xu J. ; Gao P. ; et al Nano Lett. 2017, 17, 7539. doi: 10.1021/acs.nanolett.7b03476
81	Guan G. ; Liu S. ; Cheng Y. ; Zhang Y. W. ; Han M. Y. Nanoscale 2018, 10, 10911. doi: 10.1039/c8nr02121j
82	Zhang W. ; Huynh T. ; Xiu P. ; Zhou B. ; Ye C. ; Luan B. ; Zhou R. Carbon 2015, 94, 895. doi: 10.1016/j.carbon.2015.07.075
83	Hussain T. ; Vovusha H. ; Kaewmaraya T. ; Amornkitbamrung V. ; Ahuja R. Sens. Actuators B: Chem. 2018, 255, 2713. doi: 10.1016/j.snb.2017.09.083
84	Jagvaral Y. ; He H. ; Pandey R. 2D Mater 2018, 5, 015012. doi: 10.1088/2053-1583/aa8c92
85	Shen J. ; Shi M. ; Yan B. ; Ma H. ; Li N. ; Hu Y. ; Ye M. Colloids Surf. B 2010, 81, 434. doi: 10.1016/j.colsurfb.2010.07.035
86	Li H. ; Fierens K. ; Zhang Z. ; Vanparijs N. ; Schuijs M. J. ; Steendam K. V. ; Gracia N. F. ; Rycke R. D. ; Beer T. D. ; Beuckelaer A. D. ; et al ACS Appl. Mater. Interfaces 2016, 8, 1147. doi: 10.1021/acsami.5b08963
87	Hong S. G. ; Kim J. H. ; Kim R. E. ; Kwon S. J. ; Kim D. W. ; Jung H. T. ; Dordick J. S. ; Kim J. Biotechnol. Bioproc. E 2016, 21, 573. doi: 10.1007/s12257-016-0373-4
88	Wang Z. ; Ge Z. ; Zheng X. ; Chen N. ; Peng C. ; Fan C. ; Huang Q. Nanoscale 2012, 4, 394. doi: 10.1039/c1nr11174d
89	Yang Q. ; Pan X. ; Clarke K. ; Li K. Ind. Eng. Chem. Res. 2012, 51, 310. doi: 10.1021/ie201391e
90	Liu Y. ; Tao L. Q. ; Wang D. Y. ; Zhang T. Y. ; Yang Y. ; Ren T. L. Appl. Phys. Lett. 2017, 110, 123508. doi: 10.1063/1.4978374
91	Zeng Q. ; Cheng J. ; Tang L. ; Liu X. ; Liu Y. ; Li J. ; Jiang J. Adv. Funct. Mater. 2010, 20, 3366. doi: 10.1002/adfm.201000540
92	Guo C. X. ; Zheng X. T. ; Lu Z. S. ; Lou X. W. ; Li C. M. Adv. Mater. 2010, 22, 5164. doi: 10.1002/adma.201001699
93	Al-Dirini F. ; Mohammed M. A. ; Hossain M. S. ; Hossain F. M. ; Nirmalathas A. ; Skafidas E. Nanoscale 2016, 8, 10066. doi: 10.1039/c5nr05274b
94	Zhang X. ; Wang L. ; Lu Q. ; Kaplan D. L. ACS Appl. Mater. Interfaces 2018, 10, 22924. doi: 10.1021/acsami.8b04777
95	Yang Z. ; Ge C. ; Liu J. ; Chong Y. ; Gu Z. ; Jimenez-Cruz C. A. ; Chai Z. ; Zhou R. Nanoscale 2015, 7, 18725. doi: 10.1039/c5nr01172h
96	Cheng Y. ; Koh L. D. ; Wang F. ; Li D. ; Ji B. ; Yeo J. ; Guan G. ; Han M. Y. ; Zhang Y. W. Nanoscale 2017, 9, 9181. doi: 10.1039/c7nr01428g
97	Weng Q. ; Wang B. ; Wang X. ; Hanagata N. ; Li X. ; Liu D. ; Wang X. ; Jiang X. ; Bando Y. ; Golberg D. ACS Nano 2014, 8, 6123. doi: 10.1021/nn5014808
98	Chu J. ; Shi P. ; Yan W. ; Fu J. ; Yang Z. ; He C. ; Deng X. ; Liu H. Nanoscale 2018, 10, 9547. doi: 10.1039/c8nr02538j
99	Yin W. ; Yan L. ; Yu J. ; Tian G. ; Zhou L. ; Zheng X. ; Zhang X. ; Yong Y. ; Li J. ; Gu Z. ; et al ACS Nano 2014, 8, 6922. doi: 10.1021/nn501647j
100	Yong Y. ; Zhou L. ; Gu Z. ; Yan L. ; Tian G. ; Zheng X. ; Liu X. ; Zhang X. ; Shi J. ; Cong W. ; et al Nanoscale 2014, 6, 10394. doi: 10.1039/c4nr02453b
101	Shao J. ; Xie H. ; Wang H. ; Zhou W. ; Luo Q. ; Yu X. F. ; Chu P. K. ACS Appl. Mater. Interfaces 2018, 10, 1155. doi: 10.1021/acsami.7b17117
102	Yang X. ; Wang D. ; Shi Y. ; Zou J. ; Zhao Q. ; Zhang Q. ; Huang W. ; Shao J. ; Xie X. ; Dong X. ACS Appl. Mater. Interfaces 2018, 10, 12431. doi: 10.1021/acsami.8b00276
103	Tao W. ; Ji X. ; Xu X. ; Islam M. A. ; Li Z. ; Chen S. ; Saw P. E. ; Zhang H. ; Bharwani Z. ; Guo Z. ; et al Angew. Chem. Int. Ed. 2017, 56, 11896. doi: 10.1002/anie.201703657
104	Wang K. ; Chen Q. ; Xue W. ; Li S. ; Liu Z. ACS Biomater. Sci. Eng. 2017, 3, 2325. doi: 10.1021/acsbiomaterials.7b00499
105	Zhang A. ; Li A. ; Tian W. ; Li Z. ; Wei C. ; Sun Y. ; Zhao W. ; Liu M. ; Liu J. Chem. Eur. J. 2017, 23, 11346. doi: 10.1002/chem.201701916
106	Lin L. S. ; Yang X. ; Niu G. ; Song J. ; Yang H. H. ; Chen X. Nanoscale 2016, 8, 2116. doi: 10.1039/c5nr07552a
107	Feng W. ; Chen L. ; Qin M. ; Zhou X. ; Zhang Q. ; Miao Y. ; Qiu K. ; Zhang Y. ; Hea C. Sci. Rep. 2015, 5, 17422. doi: 10.1038/srep17422
108	Sun Z. ; Xie H. ; Tang S. ; Yu X. F. ; Guo Z. ; Shao J. ; Zhang H. ; Huang H. ; Wang H. ; Chu P. K. Angew. Chem. Int. Ed. 2015, 54, 11526. doi: 10.1002/anie.201506154
109	Cheng L. ; Liu J. ; Gu X. ; Gong H. ; Shi X. ; Liu T. ; Wang C. ; Wang X. ; Liu G. ; Xing H. ; et al Adv. Mater. 2014, 26, 1886. doi: 10.1002/adma.201304497
110	Yong Y. ; Cheng X. ; Bao T. ; Zu M. ; Yan L. ; Yin W. ; Ge C. ; Wang D. ; Gu Z. ; Zhao Y. ACS Nano 2015, 9, 12451. doi: 10.1021/acsnano.5b05825
111	Li J. ; Jiang F. ; Yang B. ; Song X. R. ; Liu Y. ; Yang H. H. ; Cao D. R. ; Shi W. R. ; Chen G. N. Sci. Rep. 2013, 3, 1998. doi: 10.1038/srep01998
112	Pham V. T. ; Truong V. K. ; Quinn M. D. ; Notley S. M. ; Guo Y. ; Baulin V. A. ; Al Kobaisi M. ; Crawford R. J. ; Ivanova E. P. ACS Nano 2015, 9, 8458. doi: 10.1021/acsnano.5b03368
113	Xiong Z. ; Zhang X. ; Zhang S. ; Lei L. ; Ma W. ; Li D. ; Wang W. ; Zhao Q. ; Xing B. Ecotox. Environ. Safe. 2018, 161, 507. doi: 10.1016/j.ecoenv.2018.06.008
114	Hui L. ; Auletta J. T. ; Huang Z. ; Chen X. ; Xia F. ; Yang S. ; Liu H. ; Yang L. ACS Appl. Mater. Interfaces 2015, 7, 10511. doi: 10.1021/acsami.5b02008
115	Yin W. ; Yu J. ; Lv F. ; Yan L. ; Zheng L. R. ; Gu Z. ; Zhao Y. ACS Nano 2016, 10, 11000. doi: 10.1021/acsnano.6b05810
116	Bang G. S. ; Cho S. ; Son N. ; Shim G. W. ; Cho B. K. ; Choi S. Y. ACS Appl. Mater. Interfaces 2016, 8, 1943. doi: 10.1021/acsami.5b10136

Materials	Wavelength/nm	Photothermal conversion efficiency	Treatment target	Ref.
Bi₂Se₃	808	26.4%	Human skin fibroblast cell, HeLa cell	101
Phosphorene	660	43.6%	HeLa cell	102
Antimonene	808	45.5%	MCF-7 cell, HeLa cell	103
MoS₂	808	29.4%	3T3 cell, HeLa cell	104
MoS₂	808	Not given	HepG2 cell	105
GO	808	Not given	U87MG cell	106
MoS₂	808	27.6%	4T1 cell	107
Phosphorene	808	28.4%	C6 cell, MCF7 cell	108
WS₂	808	Not given	4T1 cell	109
WS₂	808	44.3%	HeLa cell, HepG 2 cell	110
Bi₂Se₃	808	Not given	H22 cell	111

[1]	刘华艳, 陈逸飞, 杨梦召, 顾佳俊. 二维材料基超级电容器的容量与倍率性能提升策略[J]. 物理化学学报, 2025, 41(6): 100063 - .
[2]	董鹏宇, 姜月, 杨正池, 刘立城, 李固, 文鑫洋, 王祯, 施信波, 周国富, 刘俊明, 高进伟. NbSe₂纳米片优化钙钛矿太阳能电池的埋底界面[J]. 物理化学学报, 2025, 41(3): 100029 - .
[3]	贺梦菲, 陈超, 唐月, 孟思, 王遵法, 王立煜, 行家宝, 张欣宇, 黄佳慧, 卢江波, 井红梅, 刘翔宇, 徐华. 外延生长具有厚度可调导电属性的非层状二维碲化锰纳米片用于p-型场效应晶体管和优异的接触电极[J]. 物理化学学报, 2025, 41(2): 100016 - .
[4]	邵毅宏, 沈荣晨, 王松, 李世杰, 张鹏, 李鑫. 共价有机框架中的组分工程用于定制光催化[J]. 物理化学学报, 2025, 41(12): 100176 - .
[5]	秦春玲, 陈爽, GomaaHassanien, ShenashenMohamed A., El-SaftySherif A., 刘倩, 安翠华, 刘熙俊, 邓齐波, 胡宁. 外加物理场调控二维材料的HER和OER性能[J]. 物理化学学报, 2024, 40(9): 2307059 - .
[6]	蔡宇珊, 肖方兴. MXenes基光催化剂的进展、挑战和展望[J]. 物理化学学报, 2024, 40(8): 2306048 - .
[7]	崔元映, 张金锋, 褚海亮, 孙立贤, 代凯. 铋基光催化剂在太阳能转换中的合理设计[J]. 物理化学学报, 2024, 40(12): 2405016 - .
[8]	林凯风, 钟叮, 邵嘉惠, 刘开辉, 王金焕, 左勇刚, 周旭. 二维材料复合光纤调制器件研究进展[J]. 物理化学学报, 2023, 39(10): 2306026 - .
[9]	夏洲, 邵元龙. 湿法纺制石墨烯纤维：工艺、结构、性能与智能应用[J]. 物理化学学报, 2022, 38(9): 2103046 - .
[10]	温烨烨, 任明, 邸江涛, 张锦. 烯碳材料在人工肌肉领域的应用进展[J]. 物理化学学报, 2022, 38(9): 2107006 - .
[11]	周航, 焦琨. 烯碳材料改性有机高性能纤维：制备、性能及应用[J]. 物理化学学报, 2022, 38(9): 2111041 - .
[12]	曹晓辉, 侯成义, 李耀刚, 李克睿, 张青红, 王宏志. 基于MXenes的功能纤维的制备及其在智能可穿戴领域的应用[J]. 物理化学学报, 2022, 38(9): 2204058 - .
[13]	蹇木强, 张莹莹, 刘忠范. 石墨烯纤维：制备、性能与应用[J]. 物理化学学报, 2022, 38(2): 2007093 - .
[14]	梁涛, 王斌. 层间共价增强石墨烯材料的构筑、性能与应用[J]. 物理化学学报, 2022, 38(1): 2011059 - .
[15]	王薇, 黄宇, 王震宇. 缺陷工程调控石墨相氮化碳及其光催化空气净化应用进展[J]. 物理化学学报, 2021, 37(8): 2011073 - .

二维材料“遇见”生物大分子：机遇与挑战

2D Materials Meet Biomacromolecules: Opportunities and Challenges

RichHTML

PDF

赞

可视化

摘要/Abstract

引用本文

使用本文

图/表 5

参考文献 116

相关文章 15

Metrics

推荐阅读 0