线粒体体外代谢热动力学模型及其演化优化研究

doi:10.3866/PKU.WHXB19970606

Acta Phys. -Chim. Sin. ›› 1997, Vol. 13 ›› Issue (06): 503-509.doi: 10.3866/PKU.WHXB19970606

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Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization

Xiong Ya,Pan Zheng-Jun,Wang Hong,Wu Ding-Quan,Kang Li-Shan,Qu Song-Sheng

Department of Chemistry,State Key Laboratory of Soft Engineer,Wuhan University,Wuhan 430072

Received:1996-09-22 Revised:1996-11-25 Published:1997-06-15
Contact: Qu Song-Sheng

Abstract

Abstract:

The thermokinetic equation (MTD) of mitochondrial metabolism was deduced and the relation between this equation and exponential model was examined. The technology of evolutionary computation was first introduced to the research of biological thermochemistry. The thermokinetic parameters of some mitochondrial external metabolism were globally optimized with the evolutionary computation program about MTD, which was programmed ourselves, and excellent result was obtained.

Key words: Mitochondria, Evolution computation, Thermokinetics, Global optimum, Microcalorimetry

Xiong Ya,Pan Zheng-Jun,Wang Hong,Wu Ding-Quan,Kang Li-Shan,Qu Song-Sheng. Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization[J]. Acta Phys. -Chim. Sin. 1997, 13(06), 503-509. doi: 10.3866/PKU.WHXB19970606

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Studies on the Thermokinetic Model of Mitochondrial Metabolism and its Evolutionary Optimization

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