物理化学学报 >> 2000, Vol. 16 >> Issue (06): 568-572.doi: 10.3866/PKU.WHXB20000618

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微量热法研究硒对大肠杆菌生长代谢的作用

李曦, 刘义, 吴军, 赵儒铭, 屈松生   

  1. 武汉大学化学与环境科学学院 武汉大学生命科学学院，武汉 430072|武汉工业大学材料与工程学院，武汉430070|湖北宜昌三峡学院化学系，湖北 443000
  • 收稿日期:1999-10-14 修回日期:2000-01-17 发布日期:2000-06-15
  • 通讯作者: 刘义

Microcalorimetric Study of the Action of Selenium-containing Complexes on Growth Metabolism of Escherichia coli

Li Xi, Liu Yi, Wu Jun, Zhao Ru-Ming, Qu Song-Sheng   

  1. College of Chemistry and Environment Science,College of Life Science,Wuhan University,Wuhan 430072|School of Material Science and Technology,Wuhan University of Technology,Wuhan 430070|Department of Chemistry,Hubei Three Gorge University,Hubei 443000
  • Received:1999-10-14 Revised:2000-01-17 Published:2000-06-15
  • Contact: Liu Yi

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关键词: 微量热法, 含硒络合物, 大肠杆菌, 生长代谢

Abstract:

The thermokinetic characteristics of the actions of selenium containing complexes on the growth metabolism of Escherichia coli were studied by means of microcalorimetry. It was found that at low concentration of Na2SeO3 and N, N′-methylene bisselenomorpholine promoting action on the growth of Escherichia coli, and at high concentration inhibiting action were observed but selenomorpholine had only inhibiting action. Considering both the half inhibition concentration(Ic50) and the rate constant (k), the inhibiting activity of selenium containing complexes studied is in the series of N, N′-methylene bisselenomorpholine > Na2SeO3 and selenomorpholine.

Key words: Microcalorimetry, Selenium-containing complexes, Escherichia coll, Growth metabolism