物理化学学报 >> 2011, Vol. 27 >> Issue (03): 683-688.doi: 10.3866/PKU.WHXB20110307

催化和表面科学 上一篇    下一篇

磺化碳纳米管/活性炭复合微球的制备及其对低密度脂蛋白的吸附性能

卢月美1,2, 巩前明1,2,3, 卢方平4, 梁吉1,2, 聂庆东5, 张秀梅5   

  1. 1. 清华大学机械工程系, 北京 100084;
    2. 清华大学先进成形制造教育部重点实验室, 北京 100084;
    3. 康乃尔大学材料科学与 工程系, 伊萨卡 14850, 美国;
    4. 清华大学第一附属医院肾脏科, 北京 100016;
    5. 清华大学校医院, 北京 100084
  • 收稿日期:2010-09-02 修回日期:2010-12-17 发布日期:2011-03-03
  • 通讯作者: 梁吉 E-mail:liangji@mail.tsinghua.edu.cn
  • 基金资助:

    国家自然科学基金(50602026)资助项目

Preparation of Sulfonated Carbon Nanotubes/Activated Carbon Composite Beads and Their Adsorption Capacity for Low Density Lipoprotein

LU Yue-Mei1,2, GONG Qian-Ming1,2,3, LU Fang-Ping4, LIANG Ji1,2, NIE Qing-Dong5, ZHANG Xiu-Mei5   

  1. 1. Department of Mechanical Engineering ,Tsinghua University, Beijing 100084, P. R. China;
    2. Key Laboratory for Advanced Materials Processing Technology, Ministry of Education, Tsinghua University, Beijing 100084, P. R. China;
    3. Department of Materials Science and Engineering, Cornell University, Ithaca 14850, USA;
    4. Department of Nephrology, The First Affiliated Hospital of Tsinghua University, Beijing 100016, P. R. China;
    5. Tsinghua University Hospital, Beijing 100084, P. R. China
  • Received:2010-09-02 Revised:2010-12-17 Published:2011-03-03
  • Contact: LIANG Ji E-mail:liangji@mail.tsinghua.edu.cn
  • Supported by:

    The project was supported by the National Natural Science Foundation of China (50602026).

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摘要：

采用悬浮聚合、炭化、活化制得碳纳米管/活性炭复合微球; 而后利用重氮盐偶合法将对氨基苯磺酸接枝到此复合微球上, 得到磺化碳纳米管/活性炭复合微球; 将其用于吸附血清中的低密度脂蛋白(LDL). 结果表明: 所制备的磺化碳纳米管/活性炭复合微球球形度好, 表面光洁, 中孔发达, 并且接枝有对氨基苯磺酸. 此复合微球对LDL的吸附量随着碳纳米管加入量的增加而逐渐增大; 当碳纳米管加入量为45% (w)时, LDL吸附量达6.564 mg·g-1, 是未添加碳纳米管的3.3倍. 此复合微球在作为血液灌流LDL吸附剂方面有较好的应用前景.

关键词: 碳纳米管, 复合微球, 磺化, 低密度脂蛋白, 吸附

Abstract:

Sulfonated carbon nanotubes (CNTs)/activated carbon composite beads were obtained by suspension polymerization, carbonization, activation, and further sulfonation using the diazonium salt coupling method. Adsorption of low density lipoprotein (LDL) was explored with these composite beads. The results showed that the composite beads had good sphericity, smooth surface, developed mesopores and were sulfonated by p-aminobenzenesulfonic acid. With the increase of CNTs mass ratio, the adsorption capacity of LDL increased. When the CNTs mass fraction was 45%, the amount of LDL adsorption reached 6.564 mg·g-1 and was 3.3 times as large as that of the beads without CNTs. Therefore, the composite beads have good prospects as LDL adsorbents in hemoperfusion.

Key words: Carbon nanotube, Composite bead, Sulfonated, Low density lipoprotein, Adsorption